PMID: 8981373Jan 1, 1997Paper

Spatial memory deficits in patients with unilateral damage to the right hippocampal formation

Neuropsychologia
S AbrahamsR G Morris

Abstract

Patients with unilateral temporal lobe damage resulting from intractable temporal lobe epilepsy (TLE, n = 30) or from temporal lobe resection (temporal lobectomy, TLR, n = 47) were investigated on the Nine-box Maze. The task, analogous to the radial arm maze, was designed to compare spatial mapping and working memory theories of the functions of the hippocampus. The task provides measures of spatial, object, working and reference memory, incorporated into a within subjects design. The spatial component was designed to encourage the formation of allocentric rather than egocentric spatial representations. Spatial memory deficits were found (across working and reference memory components) in both TLE and TLR patients with right temporal lobe damage, with intact spatial memory in patients with corresponding left temporal lobe damage. Performance on the matched non-spatial (object) working memory component was equal to healthy controls for all groups. However all patient groups showed a deficit on object reference memory. These findings are discussed in relation to the underlying temporal lobe pathology and particularly atrophy of the hippocampal formation. Overall, the results support the cognitive mapping theory of hippocampal fun...Continue Reading

References

Apr 1, 1979·Journal of Clinical Psychology·G E Powell
Apr 1, 1976·Experimental Neurology·J O'Keefe
Jan 11, 1992·Acta Neurologica Scandinavica. Supplementum·J Engel
Jan 1, 1992·Behavioral and Neural Biology·H EichenbaumN J Cohen
Jul 1, 1991·Hippocampus·L Nadel
Dec 1, 1991·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·C HelmstaedterC E Elger
Mar 1, 1991·Journal of Clinical and Experimental Neuropsychology·R RauschC M Ary
Jan 1, 1991·Neuropsychologia·M A Shoqeirat, A R Mayes
Jan 1, 1991·Neuropsychologia·A R MayesC MacDonald
Sep 1, 1989·The Japanese Journal of Psychiatry and Neurology·K MatsudaM Seino
Jan 1, 1989·Neuropsychologia·L H GoldsteinC E Polkey
Jun 1, 1988·Behavioral Neuroscience·K C Raffaele, D S Olton
Jan 1, 1987·Experimental Brain Research·J O'Keefe, A Speakman
Jul 1, 1986·Behavioural Brain Research·A M Fagan, D S Olton
May 1, 1985·The British Journal of Clinical Psychology·G E PowellT McMillan
Feb 1, 1986·Behavioural Brain Research·J P AggletonJ N Rawlins
Feb 1, 1985·The Quarterly Journal of Experimental Psychology. B, Comparative and Physiological Psychology·D Gaffan, R C Saunders
Aug 1, 1973·The Journal of Nervous and Mental Disease·H Glowinski
Apr 1, 1983·Epilepsia·P LoiseauP L Morselli
Jun 24, 1982·Nature·R G MorrisJ O'Keefe
Jan 1, 1981·Experimental Brain Research·D S Olton, W A Feustle
Jan 1, 1981·Neuropsychologia·M L Smith, B Milner

❮ Previous
Next ❯

Citations

Mar 11, 1999·Annals of Neurology·C J PlonerC Pierrot-Deseilligny
Jan 25, 2003·Hippocampus·John A KingJohn O'Keefe
May 13, 2005·Hippocampus·Valerie TreyerArmin Schnider
Nov 15, 2007·Current Neurology and Neuroscience Reports·Adam L Hartman, Ronald P Lesser
Jan 1, 1996·Brain Research Bulletin·R G MorrisJ D Feigenbaum
Apr 20, 2004·Neuropsychologia·Katerina StepankovaVéronique D Bohbot
Nov 26, 1999·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·J S HoldstockN Roberts
Mar 20, 2001·Neuropsychologia·C L WorsleyR G Morris
Apr 27, 2000·Neuroscience and Biobehavioral Reviews·A Collie, P Maruff
Feb 13, 2001·Neuroscience and Biobehavioral Reviews·H P LippG Dell'Omo
Jun 26, 2001·Brain Research. Brain Research Reviews·R P KesselsA Postma
Oct 19, 2002·Behavioural Brain Research·Anna GagliardoGiorgio Vallortigara
Jun 25, 2003·Brain and Cognition·Linda M PentlandStephen J Wood
Jan 22, 2004·Brain and Cognition·Nancy D Chiaravalloti, Guila Glosser
Feb 6, 2002·Brain Research Bulletin·Robert T GerlaiHeidi S Phillips
Aug 15, 2006·Journal of the International Neuropsychological Society : JINS·Regina McConleyEdward Faught
May 25, 2007·Journal of the International Neuropsychological Society : JINS·Anthony C KneeboneDavid W Loring
Apr 29, 2004·Behavioral Neuroscience·Meghan C Kahn, Verner P Bingman
Feb 25, 2005·Behavioral Neuroscience·Agnès LacreuseJames G Herndon
Aug 5, 2004·Neuropsychology·David M ParslowRobin G Morris
Aug 5, 2004·Neuropsychology·Janet D Feigenbaum, Robin G Morris
May 1, 2001·The European Journal of Neuroscience·A GagliardoG Vallortigara
Mar 11, 2000·The European Journal of Neuroscience·A Nowicka, J L Ringo
Oct 20, 2006·Journal of Clinical and Experimental Neuropsychology·Catherine M Diaz-AsperAnthony Caputy
Sep 3, 2008·Journal of Clinical and Experimental Neuropsychology·Jessica S ChapinImad M Najm
Mar 3, 2009·Brain : a Journal of Neurology·Michael M Saling
Jan 30, 2013·Toxicological Sciences : an Official Journal of the Society of Toxicology·Deborah A Cory-SlechtaJoshua L Allen
Nov 22, 1997·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·B MilnerJ Crane
Oct 25, 2002·Journal of Neurology, Neurosurgery, and Psychiatry·S DupontM Baulac

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.