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Spatial model predicts dispersal and cell turnover cause reduced intra-tumor heterogeneity

bioRxiv

Mar 20, 2015

Bartłomiej WaclawMartin A. Nowak

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Abstract

Most cancers in humans are large, measuring centimeters in diameter, composed of many billions of cells. An equivalent mass of normal cells would be highly heterogeneous as a result of the mutations that occur during each cell division. What is remarkable about cancers is their homogene...read more

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  • Spatial model predicts dispersal and cell turnover cause reduced intra-tumor heterogeneity

    bioRxiv

    Mar 20, 2015

    Bartłomiej WaclawMartin A. Nowak

    PMID: 990016824

    DOI: 10.1101/016824

    Abstract

    Most cancers in humans are large, measuring centimeters in diameter, composed of many billions of cells. An equivalent mass of normal cells would be highly heterogeneous as a result of the mutations that occur during each cell division. What is remarkable about cancers is their homogene...read more

    10
    228
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