Spatial representation in the hippocampal formation: a history

Nature Neuroscience
Edvard I MoserBruce L McNaughton

Abstract

Since the first place cell was recorded and the cognitive-map theory was subsequently formulated, investigation of spatial representation in the hippocampal formation has evolved in stages. Early studies sought to verify the spatial nature of place cell activity and determine its sensory origin. A new epoch started with the discovery of head direction cells and the realization of the importance of angular and linear movement-integration in generating spatial maps. A third epoch began when investigators turned their attention to the entorhinal cortex, which led to the discovery of grid cells and border cells. This review will show how ideas about integration of self-motion cues have shaped our understanding of spatial representation in hippocampal-entorhinal systems from the 1970s until today. It is now possible to investigate how specialized cell types of these systems work together, and spatial mapping may become one of the first cognitive functions to be understood in mechanistic detail.

References

Feb 10, 1978·Archives of Orthopaedic and Trauma Surgery·O J Fasting
Apr 14, 1978·Experimental Brain Research·J O'Keefe, D H Conway
Apr 30, 1976·Science·T W BergerR F Thompson
Apr 1, 1976·Experimental Neurology·J O'Keefe
Jul 1, 1991·Hippocampus·J L Kubie, R U Muller
Feb 1, 1990·Cognition·C R Gallistel, R Gelman
Sep 1, 1989·Quarterly Journal of Experimental Physiology : an International Journal of the Physiological Society·J F Stein
Jan 1, 1987·Experimental Brain Research·J O'Keefe, A Speakman
Jul 1, 1971·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·D Marr
Sep 1, 1972·Journal of Neurophysiology·M Segal, J Olds
Jan 1, 1964·Journal of Theoretical Biology·J S Barlow
Oct 1, 1983·Brain Research·G BuzsákiC H Vanderwolf
Jul 29, 1994·Science·M A Wilson, B L McNaughton
Sep 1, 1993·Journal of Clinical and Experimental Neuropsychology·G A BakerP Slade
Aug 20, 1993·Science·M A Wilson, B L McNaughton
Jan 1, 1995·Hippocampus·E T Rolls, S M O'Mara
Jan 1, 1996·Hippocampus·D S Touretzky, A D Redish
Jan 1, 1997·Hippocampus·A D Redish, D S Touretzky
Jul 17, 1997·Nature·C A BarnesB L McNaughton
Aug 1, 1997·The European Journal of Neuroscience·E T RollsP Georges-François
Nov 22, 1997·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·R A Andersen
Jan 10, 1998·Experimental Brain Research·K J JefferyJ M O'Keefe

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Citations

Mar 7, 2018·Experimental Brain Research·Vivekanand Pandey VimalPaul DiZio
Jul 29, 2018·The European Journal of Neuroscience·Nicola Solari, Balázs Hangya
Nov 24, 2018·Science·Cheng WangJames J Knierim
Feb 12, 2019·Nature·Ravikrishnan P JayakumarJames J Knierim
Jul 25, 2019·Hippocampus·Jørgen Sugar, May-Britt Moser
Jul 30, 2019·ELife·Lu ZhangAnnabelle C Singer
Oct 23, 2019·Nutritional Neuroscience·Valentín Peñaloza-SanchoAlexies Dagnino-Subiabre
Oct 2, 2019·Biological cybernetics·Fangwen YuMichael Milford
Oct 28, 2019·Brain Structure & Function·Thiago F A França, José M Monserrat
Dec 7, 2019·Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition·Joenilton Saturnino Cazé Da SilvaBernardino Fernández-Calvo
Nov 20, 2019·Nature Human Behaviour·Jacob L S BellmundChristian F Doeller
Mar 3, 2020·Developmental Psychobiology·Daniil P AksenovAlexander Drobyshevsky
Apr 21, 2020·Cyberpsychology, Behavior and Social Networking·Giuseppe Riva, Brenda K Wiederhold
Jan 11, 2020·Cerebral Cortex·Carlos Del Rio-BermudezMark S Blumberg
Apr 29, 2020·Neural Computation·Weishun ZhongArvind Murugan
Jul 15, 2020·Journal of Cognitive Neuroscience·Louis N Irwin, Brian A Irwin
Sep 30, 2020·Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association·Sonja SiegelIlonka Kreitschmann-Andermahr
Mar 30, 2019·Science·Charlotte N BoccaraJozsef Csicsvari
Nov 20, 2019·Cognitive Science·Kai Hamburger, Markus Knauff
Jun 30, 2019·Scientific Reports·Danica HilliardShu-Chen Li
Mar 27, 2019·Nature Neuroscience·Richard J GardnerEdvard I Moser
Jan 16, 2019·Nature Neuroscience·Matthew L Shapiro
Mar 6, 2019·Nature Reviews. Neuroscience·Guosong Hong, Charles M Lieber
Jan 29, 2020·Proceedings of the National Academy of Sciences of the United States of America·Larry W Swanson, Joel D Hahn
Mar 12, 2020·Frontiers in Behavioral Neuroscience·James BlokCatherine A Leamey
Aug 10, 2020·Molecular Neurobiology·Jordi DuranJoan J Guinovart
Jun 28, 2020·Nature Communications·Matthias NauChristian F Doeller
Sep 10, 2020·Frontiers in Systems Neuroscience·Louis N Irwin
Sep 8, 2018·Frontiers in Cellular Neuroscience·Melville J WohlgemuthCynthia F Moss
Mar 30, 2019·Science·Rodrigo Quian Quiroga
Nov 10, 2018·Science·Jacob L S BellmundChristian F Doeller
Nov 19, 2019·Frontiers in Neural Circuits·Jean BlouinMartin Simoneau
Mar 21, 2020·Nature Communications·Yuan HanJelena Radulovic
Aug 23, 2019·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·Samantha Hughes, Tansu Celikel

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