Spatially restricted dental regeneration drives pufferfish beak development

Proceedings of the National Academy of Sciences of the United States of America
Alexandre P ThieryGareth J Fraser

Abstract

Vertebrate dentitions are extraordinarily diverse in both morphology and regenerative capacity. The teleost order Tetraodontiformes exhibits an exceptional array of novel dental morphologies, epitomized by constrained beak-like dentitions in several families, i.e., porcupinefishes, three-toothed pufferfishes, ocean sunfishes, and pufferfishes. Modification of tooth replacement within these groups leads to the progressive accumulation of tooth generations, underlying the structure of their beaks. We focus on the dentition of the pufferfish (Tetraodontidae) because of its distinct dental morphology. This complex dentition develops as a result of (i) a reduction in the number of tooth positions from seven to one per quadrant during the transition from first to second tooth generations and (ii) a dramatic shift in tooth morphogenesis following the development of the first-generation teeth, leading to the elongation of dental units along the jaw. Gene expression and 1,1'-Dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate (DiI) lineage tracing reveal a putative dental epithelial progenitor niche, suggesting a highly conserved mechanism for tooth regeneration despite the development of a unique dentition. MicroCT analysis r...Continue Reading

References

Dec 10, 1997·Mechanisms of Development·I Thesleff, P Sharpe
Nov 14, 2002·Microscopy Research and Technique·Jean-Yves SireAnn Huysseune
Oct 12, 2004·Annual Review of Cell and Developmental Biology·Catriona Y Logan, Roel Nusse
Jan 15, 2005·Developmental Biology·Tomoyo SasakiYang Chai
May 6, 2008·Developmental Biology·Marcela BuchtováJoy M Richman
Jul 16, 2008·BMC Biology·Gareth J FraserJ Todd Streelman
Jan 22, 2009·Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution·Moya M SmithThimios A Mitsiadis
Feb 5, 2010·Current Biology : CB·Günter P Wagner, Vincent J Lynch
Sep 21, 2010·Developmental Biology·Gregory R Handrigan, Joy M Richman
Feb 11, 2011·Genesis : the Journal of Genetics and Development·Joy M Richman, Gregory R Handrigan
Mar 24, 2012·Journal of Dental Research·M BuchtováA S Tucker
May 9, 2012·Proceedings of the National Academy of Sciences of the United States of America·Gareth J FraserMoya M Smith
Sep 6, 2012·Development·Jukka Jernvall, Irma Thesleff
Feb 21, 2013·Developmental Biology·Gareth J FraserJ Todd Streelman
May 15, 2013·Proceedings of the National Academy of Sciences of the United States of America·Ping WuCheng-Ming Chuong
Jun 4, 2013·Molecular Phylogenetics and Evolution·Francesco SantiniMichael E Alfaro
Jan 11, 2014·Seminars in Cell & Developmental Biology·Abigail S Tucker, Gareth J Fraser
Jul 17, 2015·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Andrew H JheonOphir D Klein
Sep 29, 2015·Scientific Reports·Guilherme M XavierCynthia L Andoniadou
Oct 21, 2015·Proceedings of the National Academy of Sciences of the United States of America·Ryan F BloomquistJ Todd Streelman
Feb 5, 2016·Developmental Biology·Liam J RaschGareth J Fraser
Dec 9, 2016·Proceedings of the National Academy of Sciences of the United States of America·Kyle J MartinGareth J Fraser
Mar 1, 1982·Journal of Morphology·Roberto D AndreucciJosé Carneiro

❮ Previous
Next ❯

Citations

Apr 20, 2018·Molecular Biology and Evolution·Leon HilgersThomas von Rintelen
Nov 20, 2018·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Atukorallaya Devi Sewvandini AtukoralaRavindra Ratnayake
Aug 21, 2019·Proceedings of the National Academy of Sciences of the United States of America·Ryan F BloomquistJ Todd Streelman
Jun 14, 2020·Integrative and Comparative Biology·C Darrin HulseyGareth J Fraser
Jul 15, 2020·Integrative and Comparative Biology·Gareth J FraserAlexandre P Thiery
Jan 29, 2021·Frontiers in Cell and Developmental Biology·Vladimír SoukupRobert Cerny
Jun 2, 2021·ELife·Daniel J PaluhDavid C Blackburn
Oct 22, 2021·Evolution; International Journal of Organic Evolution·Daniel J PaluhDavid C Blackburn

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adult Stem Cells

Adult stem cells reside in unique niches that provide vital cues for their survival, self-renewal, and differentiation. They hold great promise for use in tissue repair and regeneration as a novel therapeutic strategies. Here is the latest research.

Biomechanics

Biomechanics examines the generation of internal forces within the body and investigates the effects and control of forces that act on or are produced on tissues. Here are the latest discoveries.