Spatio-Temporal Dynamics of Tick-Borne Diseases in North-Central Wisconsin from 2000-2016

International Journal of Environmental Research and Public Health
Austin RauJesse D Berman

Abstract

Lyme disease is a well-recognized public health problem in the USA, however, other tick-borne diseases also have major public health impacts. Yet, limited research has evaluated changes in the spatial and temporal patterns of non-Lyme tick-borne diseases within endemic regions. Using laboratory data from a large healthcare system in north-central Wisconsin from 2000-2016, we applied a Kulldorf's scan statistic to analyze spatial, temporal and seasonal clusters of laboratory-positive cases of human granulocytic anaplasmosis (HGA), babesiosis, and ehrlichiosis at the county level. Older males were identified as the subpopulation at greatest risk for non-Lyme tick-borne diseases and we observed a statistically significant spatial and temporal clustering of cases (p < 0.05). HGA risk shifted from west to east over time (2000-2016) with a relative risk (RR) ranging from 3.30 to 11.85, whereas babesiosis risk shifted from south to north and west over time (2004-2016) with an RR ranging from 4.33 to 4.81. Our study highlights the occurrence of non-Lyme tick-borne diseases, and identifies at-risk subpopulations and shifting spatial and temporal heterogeneities in disease risk. Our findings can be used by healthcare providers and public...Continue Reading

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Citations

Nov 21, 2020·Clinical Practice and Cases in Emergency Medicine·Rebecca J RubensteinLaura J Bontempo
Nov 18, 2021·Pathogens and Global Health·Solomon Ngutor KarshimaMusa Isiyaku Ahmed

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Methods Mentioned

BETA
PCR

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ArcGIS World Geocoding Services
R
SatScan
ArcGIS Pro
ArcGIS Pro ArcGIS Pro
QGIS
Google Maps
R Foundation for Statistical Computing

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Babesiosis is caused by parasites of the genus babesia, which are transmitted in nature by the bite of an infected tick. Discover the latest research on babesiosis here.

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Babesiosis is caused by parasites of the genus babesia, which are transmitted in nature by the bite of an infected tick. Discover the latest research on babesiosis here.

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