Spatiotemporal development of the embryonic nervous system of Saccoglossus kowalevskii

Developmental Biology
Doreen Cunningham, Elena Silva Casey

Abstract

Defining the organization and temporal onset of key steps in neurogenesis in invertebrate deuterostomes is critical to understand the evolution of the bilaterian and deuterostome nervous systems. Although recent studies have revealed the organization of the nervous system in adult hemichordates, little attention has been paid to neurogenesis during embryonic development in this third major phylum of deuterostomes. We examine the early events of neural development in the enteropneust hemichordate Saccoglossus kowalevskii by analyzing the expression of 11 orthologs of key genes associated with neurogenesis in an expansive range of bilaterians. Using in situ hybridization (ISH) and RT-PCR, we follow the course of neural development to track the transition of the early embryonic diffuse nervous system to the more regionalized midline nervous system of the adult. We show that in Saccoglossus, neural progenitor markers are expressed maternally and broadly encircle the developing embryo. An increase in their expression and the onset of pan neural markers, indicate that neural specification occurs in late blastulae - early gastrulae. By mid-gastrulation, punctate expression of markers of differentiating neurons encircling the embryo in...Continue Reading

References

Mar 24, 2000·Trends in Genetics : TIG·Y KamachiH Kondoh
Nov 21, 2000·Molecular and Cellular Neurosciences·H A Burgess, O Reiner
Feb 17, 2001·Development Genes and Evolution·T KawashimaK W Makabe
Dec 18, 2001·Science·J P HuelsenbeckJ P Bollback
Apr 12, 2002·Journal of Neuroscience Research·Nora Perrone-Bizzozero, Federico Bolognani
Aug 13, 2003·Bioinformatics·Fredrik Ronquist, John P Huelsenbeck
Sep 2, 2003·Neuron·Victoria GrahamLarysa Pevny
Oct 1, 2003·Nature Neuroscience·Magdalena BylundJonas Muhr
Jan 14, 2005·Bioinformatics·Federico AbascalDavid Posada
Sep 8, 2005·Brain Research Bulletin·Elia Benito-GutiérrezJordi Garcia-Fernàndez
Jan 24, 2006·Nature Reviews. Neuroscience·Angeliki Louvi, Spyros Artavanis-Tsakonas
Mar 24, 2006·Journal of Cell Science·Antonia RattiVincenzo Silani
Nov 23, 2006·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Alfonso Lavado, Guillermo Oliver
Jun 23, 2007·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Kyle R Brimacombe, Andrea N Ladd
Oct 12, 2007·Cellular and Molecular Life Sciences : CMLS·A PascaleA Quattrone
Nov 13, 2007·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Christian BergerGerhard M Technau
Jan 24, 2008·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Kamana MisraMichael P Matise
Nov 13, 2008·Genesis : the Journal of Genetics and Development·Federico D BrownBillie J Swalla
Jun 30, 2009·Current Biology : CB·Marc NomaksteinskyJean-François Brunet
Sep 15, 2009·Birth Defects Research. Part C, Embryo Today : Reviews·Crystal D RogersElena S Casey
Jul 29, 2010·Journal of Morphology·Sabrina Kaul, Thomas Stach
Dec 15, 2010·Developmental Biology·Tenley C ArcherElena S Casey
Jun 17, 2011·Proceedings. Biological Sciences·J Andrew GillisChristopher J Lowe
Aug 11, 2011·Development·Lynne M AngererRobert D Burke
Sep 29, 2012·Genes & Development·Valérie HilgersMichael Levine
Jan 25, 2013·Development·Stephen A GreenChristopher J Lowe

❮ Previous
Next ❯

Citations

Dec 3, 2014·Developmental Biology·Francisco Monjo, Rafael Romero
Nov 5, 2014·Genesis : the Journal of Genetics and Development·Robert D BurkeValerie J Taylor
Nov 26, 2015·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Nicholas D Holland
Oct 9, 2015·EvoDevo·Giovanni AnnonaSalvatore D'Aniello
Aug 1, 2015·Organisms, Diversity & Evolution·Sabrina Kaul-StrehlowAndreas Wanninger
Feb 25, 2015·Developmental Cell·Volker Hartenstein, Angelika Stollewerk
Jun 22, 2016·Current Opinion in Genetics & Development·Kuni Tagawa
Jul 9, 2016·Current Opinion in Genetics & Development·Maria Ina ArnoneRossella Annunziata
Nov 11, 2015·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Linda Z Holland
Feb 2, 2018·Cellular and Molecular Life Sciences : CMLS·Elisabeth ZiegerMichael Schubert
Apr 24, 2015·Nature·Nicholas D HollandPeter W H Holland
Jun 25, 2020·Journal of Pediatric Ophthalmology and Strabismus·Hansell SotoArun D Singh
Nov 11, 2018·Development·David R McClayStacy L Feinberg
Mar 7, 2020·Frontiers in Neuroscience·Arturo Ortega, Tatiana N Olivares-Bañuelos
Oct 15, 2019·Developmental Biology·José M Martín-Durán, Andreas Hejnol
Feb 20, 2015·The Journal of Experimental Biology·Linda Z Holland

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adult Stem Cells

Adult stem cells reside in unique niches that provide vital cues for their survival, self-renewal, and differentiation. They hold great promise for use in tissue repair and regeneration as a novel therapeutic strategies. Here is the latest research.

Calcium & Bioenergetics

Bioenergetic processes, including cellular respiration and photosynthesis, concern the transformation of energy by cells. Here is the latest research on the role of calcium in bioenergetics.