Spatiotemporal property analysis of birth defects in Wuxi, China

Biomedical and Environmental Sciences : BES
Jilei WuXiaoying Zheng

Abstract

To describe the temporal trends and spatial patterns of birth defects occurring in Wuxi, a developed region of China. Wavelet analysis was used to decompose the temporal trends of birth defect prevalence based on the birth defect rates over the past 16 years. Birth defect cases with detailed personal and family information were geo-coded and the relative risk in each village was calculated. General G statistic was used to test the spatial property with different scales. Wavelet analysis showed an increasing temporal trend of birth defects in this region. Clustering analysis revealed that changes continued in the spatial patterns with different scales. Wuxi is confronted with severe challenges to reduce birth defect prevalence. The risk factors are stable and show no change with spatial scale but an increasing temporal trend. Interventions should be focused on villages with a higher prevalence of birth defects.

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Citations

Nov 9, 2012·BMC Public Health·Lianfa LiJun Wu
Jul 1, 2014·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Mei YangYukai Du
May 26, 2017·Journal of Gynecology Obstetrics and Human Reproduction·M AlouiR Marrakchi

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