PMID: 6880237Feb 1, 1983

Species differences, influence of dose and application on biotransformation of phenol in fish

Xenobiotica; the Fate of Foreign Compounds in Biological Systems
R Nagel

Abstract

1. The metabolism of phenol in goldfish (Carassius auratus), rainbow trout (Salmo gairdneri) and goldenorfe ide (Leuciscus ideus melanotus) was compared. All three species produced phenyl sulphate, quinol sulphate and phenyl glucuronide. 2. The dose dependence of metabolism of phenol in goldfish was investigated. When the concn. of phenol was increased from 0.2 to 2 mg/l medium, that glucuronylated increased from 7 to 16% and that sulphated decreased from 63 to 47%. 3. The influence of mode of exposure on metabolism of phenol in goldfish was examined. Dietary exposure and uptake from medium was compared with i.p. injection. There was less metabolism in the order: dietary exposure greater than uptake from medium greater than injection.

References

Dec 1, 1979·Environmental Health Perspectives·H P HoenschF Hartmann
Mar 1, 1979·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·J KaoJ K Faulkner
Dec 1, 1979·Environmental Health Perspectives·R S Chhabra
Feb 1, 1983·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·R Nagel, K Urich
Mar 1, 1981·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·P J Layiwola, D F Linnecar
Jan 1, 1980·Archives of Environmental Contamination and Toxicology·G M DeGraeveH L Bergman
Jan 1, 1980·Archives of Environmental Contamination and Toxicology·D J CallP Y Lu

Citations

Feb 1, 1989·Bulletin of Environmental Contamination and Toxicology·T KasokatK Urich
Nov 14, 2006·General and Comparative Endocrinology·K Gontier-LatonnelleC Bennetau-Pelissero
Aug 6, 2004·Toxicology Letters·Bozena Bukowska, Sylwia Kowalska
Apr 1, 1985·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·J Beyer, G Frank
Oct 1, 1987·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·T KasokatK Urich
Jan 1, 1989·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·G R Stehly, W L Hayton
Nov 1, 1987·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·G GörgeK Urich
Apr 19, 2008·Drug Metabolism and Disposition : the Biological Fate of Chemicals·John W NicholsC T Jenson

Related Concepts

Metabolic Biotransformation
Dose-Response Relationship, Drug
Nutrients
Goldfish
Injections, Intraperitoneal
Phenols
Salvelinus

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