PMID: 6164162Nov 1, 1980Paper

Species specificity study of swine leukocyte interferon on different cell cultures

Voprosy virusologii
L N Pokidysheva, L A Lavrukhina

Abstract

The antiviral effect of swine leukocyte interferon was studied in cell cultures of different origins. Swine leukocyte interferon was demonstrated to protect human diploid fibroblasts. The cultures of primarily trypsinized mouse embryo fibroblasts and continuous bovine embryo tracheal cells are as sensitive to swine leukocyte interferon as human diploid cells. Studies of the age sensitivity of mouse fibroblast tissues to swine interferon showed the tissue sensitivity to interferon to decline markedly with age.

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