Species-Wide Transposable Element Repertoires Retrace the Evolutionary History of the Saccharomyces cerevisiae Host.

Molecular Biology and Evolution
Claudine Bleykasten-GrosshansJoseph Schacherer

Abstract

Transposable elements (TE) are an important source of genetic variation with a dynamic and content that greatly differ in a wide range of species. The origin of the intraspecific content variation is not always clear and little is known about the precise nature of it. Here, we surveyed the species-wide content of the Ty LTR-retrotransposons in a broad collection of 1,011 Saccharomyces cerevisiae natural isolates to understand what can stand behind the variation of the repertoire that is the type and number of Ty elements. We have compiled an exhaustive catalog of all the TE sequence variants present in the S. cerevisiae species by identifying a large set of new sequence variants. The characterization of the TE content in each isolate clearly highlighted that each subpopulation exhibits a unique and specific repertoire, retracing the evolutionary history of the species. Most interestingly, we have shown that ancient interspecific hybridization events had a major impact in the birth of new sequence variants and therefore in the shaping of the TE repertoires. We also investigated the transpositional activity of these elements in a large set of natural isolates, and we found a broad variability related to the level of ploidy as wel...Continue Reading

References

Feb 1, 1991·Proceedings of the National Academy of Sciences of the United States of America·M J Curcio, D J Garfinkel
Feb 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·W S Hu, H M Temin
Jul 18, 1995·Proceedings of the National Academy of Sciences of the United States of America·M NegroniH Buc
Apr 5, 2002·Journal of Virology·Joseph F LawlerJill B Keeney
Feb 3, 2005·Genetics·David J GarfinkelSharon P Moore
Aug 12, 2005·Cytogenetic and Genome Research·P Lesage, A L Todeschini
Dec 19, 2006·PLoS Genetics·Abram GabrielMaitreya J Dunham
Nov 7, 2007·Nature Reviews. Genetics·Thomas WickerAlan H Schulman
May 20, 2009·Bioinformatics·Heng Li, Richard Durbin
Jun 10, 2009·Bioinformatics·Heng LiUNKNOWN 1000 Genome Project Data Processing Subgroup
Nov 14, 2012·Annual Review of Genetics·Cheng Ran Lisa HuangJef D Boeke
Dec 12, 2012·PloS One·Martin CarrCasey M Bergman
Jun 19, 2013·BMC Genomics·Claudine Bleykasten-GrosshansJoseph Schacherer
Mar 4, 2014·PloS One·Doris VelaMaría Pilar García Guerreiro
Jan 23, 2015·Journal of Virology·Agniva SahaDavid J Garfinkel
Jun 25, 2015·Microbiology Spectrum·M Joan CurcioPascale Lesage
Oct 10, 2015·PLoS Genetics·Jessica M TuckerDavid J Garfinkel
Dec 10, 2015·Current Genetics·David J GarfinkelKatarzyna J Purzycka
Jun 4, 2016·ELife·Leandro QuadranaVincent Colot
Jun 19, 2016·G3 : Genes - Genomes - Genetics·Yuan O ZhuDmitri A Petrov
Sep 10, 2016·Cell·Brigida GalloneKevin J Verstrepen
Apr 11, 2017·Viruses·Leszek BłaszczykKatarzyna J Purzycka
Apr 13, 2018·Nature·Jackson PeterJoseph Schacherer
Jul 2, 2018·Genes & Genomics·Min-Jin HanHua-Hao Zhang

❮ Previous
Next ❯

Related Concepts

Related Feeds

Antibody Repertoire Diversity

Antibody repertoire diversity and its role during natural infection is a prerequisite for molecular and structural elucidation of functionally protective immunity. Discover the latest insights into antibody diversity here.