PMID: 3771318Nov 1, 1986Paper

Specific absorption rate and tissue temperature in local hyperthermia

International Journal of Radiation Oncology, Biology, Physics
H GriffithsR M Davies

Abstract

Specific absorption rate (SAR) and tissue temperature were measured for a total of 83 treatments in 33 patients who received local hyperthermia treatment for cancer. The patients were grouped into three categories according to tumor size. Hyperthermia was induced by 13.56 MHz electromagnetic energy applied using capacitive coupling. A method is described for evaluating SAR from the tissue temperature traces at any time in the treatment when a step change is made in applied power. The method is possible only if the temperature traces are free from interference and the total power delivered to the patient is monitored. Mean values of SAR ranged from 4.6 to 89 W kg-1 depending on the treatment site. Satisfactory heating was achieved for superficial tumors, with temperatures greater than 42 degrees C being recorded in 69% of treatments. For axillary nodes only 4% of treatments exceeded 42 degrees C. For cervix tumors an idealized tumor model was used to estimate tumor temperature from the temperature and SAR measured in the adjacent normal tissue. From the model it appears necessary either to raise the systemic temperature to 40 degrees C or to increase the SAR by at least a factor of 4 to obtain a temperature of 42 degrees C in a ...Continue Reading

References

Feb 1, 1985·The British Journal of Radiology·H GriffithsI J Kerby
Dec 1, 1983·International Journal of Radiation Oncology, Biology, Physics·S HalacT C Cetas
Jan 1, 1984·IEEE Transactions on Bio-medical Engineering·P F Turner
Mar 1, 1981·International Journal of Radiation Oncology, Biology, Physics·I A BrezovichD B Richards
Jun 1, 1980·International Journal of Radiation Oncology, Biology, Physics·W T JoinesD J Schaefer
Jun 1, 1980·International Journal of Radiation Oncology, Biology, Physics·R Strang, J Patterson

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Citations

Sep 1, 1993·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·A A De LeeuwJ J Lagendijk
Mar 1, 1990·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·R B Roemer
Jan 1, 1987·Clinical Physics and Physiological Measurement : an Official Journal of the Hospital Physicists' Association, Deutsche Gesellschaft Für Medizinische Physik and the European Federation of Organisations for Medical Physics·H Griffiths, A Ahmed
Sep 1, 1988·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·J J LagendijkJ Schipper

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