Specific and non-specific enzymes for furanosyl-containing conjugates: biosynthesis, metabolism, and chemo-enzymatic synthesis

Carbohydrate Research
Ilona ChlubnováVincent Ferrières

Abstract

There is no doubt now that the synthesis of compounds of varying complexity such as saccharides and derivatives thereof continuously grows with enzymatic methods. This review focuses on recent basic knowledge on enzymes specifically involved in the biosynthesis and degradation of furanosyl-containing polysaccharides and conjugates. Moreover, and when possible, biocatalyzed approaches, alternative to standard synthesis, will be detailed in order to strengthen the high potential of these biocatalysts to go further with the preparation of rare furanosides. Interesting results will be also proposed with chemo-enzymatic processes based on nonfuranosyl-specific enzymes.

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Citations

Oct 18, 2012·Chemical Reviews·Hashem A TahaTodd L Lowary
Dec 14, 2016·Bioorganic & Medicinal Chemistry Letters·Laurent LegentilVincent Ferrières
Feb 16, 2016·Bioorganic & Medicinal Chemistry Letters·Ilona ChlubnováVincent Ferrières
Jul 2, 2015·Organic & Biomolecular Chemistry·Yari CabezasVincent Ferrières
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Dec 18, 2013·Organic Letters·Ryan B Snitynsky, Todd L Lowary

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