Specific Antibody Immunodeficiency Presenting With Streptococcal pneumonia -Induced Spontaneous Bacterial Peritonitis

Allergy & Rhinology
Jack JeskeyRobert Hostoffer

Abstract

Specific antibody immunodeficiency (SAD) is a primary immunodeficiency disorder characterized by normal levels of serum immunoglobulins (IgG, IgA, and IgM) associated with a dysfunctional immune response. SAD is associated with recurrent infections in the setting of an insufficient response to polysaccharide vaccinations. Streptococcus pneumoniae is a well-established cause of respiratory infections in SAD. However, there has been a paucity of evidence of pneumococcal peritonitis in SAD patients, being reported as spontaneous in acquired immunodeficiency such as AIDS. We report the first case of S. pneumoniae-induced peritonitis as the presenting sign for SAD.

References

Oct 26, 2006·International Journal of STD & AIDS·Constantine AlifrangisDuncan Churchill
Dec 19, 2014·Clinical and Vaccine Immunology : CVI·Thomas M Daly, Harry R Hill
Jun 8, 2017·Frontiers in Immunology·Elena PerezMark Ballow
Sep 1, 2018·The Journal of Allergy and Clinical Immunology·Federica PulvirentiIsabella Quinti
Mar 16, 2019·Microbiology Spectrum·Allister J LoughranElaine I Tuomanen

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