Specific antioxidant reactions to oxidative stress promoted by natural organic matter in two amphipod species from Lake Baikal

Environmental Toxicology
Maxim A TimofeyevC E W Steinberg

Abstract

Aquatic organisms are exposed to a variety of natural chemical stressors such as humic substances. The aim of this study was to investigate the mode of action of natural organic matter (NOM, roughly 80% of which is humic substances) on two freshwater amphipods from Lake Baikal, Eulimnogammarus verrucosus (Gerstf.) and Eulimnogammarus cyaneus (Dyb.), in order to assess the potential oxidative stress of NOM impact. Chosen as oxidative stress markers were lipid peroxidation and cell internal hydrogen peroxide level as well as peroxidase, catalase, and glutathione S-transferase activities. Exposure of amphipods to NOM caused a significant increase in lipid peroxidation but a concomitant decrease in hydrogen peroxide concentration, and peroxidase and (to a lesser degree) glutathione S-transferase activities. An interim increase of catalase activity was observed. A possible reason for the decrease in major antioxidant enzyme activity is exhaustion of the reservoir of reduced substrates in the first stage of the antioxidant defense reaction. Despite the inhibition of major antioxidant enzymes, the studied amphipods were able to successfully resist the NOM oxidative impact and, at low NOM concentrations, to combat lipid peroxidation pr...Continue Reading

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Citations

Jul 25, 2009·Environmental Science and Pollution Research International·Darya S BedulinaChristian E W Steinberg
Feb 9, 2011·Environmental Science and Pollution Research International·Albert L SuhettVinicius F Farjalla
Jul 24, 2014·Environmental Science and Pollution Research International·Marina V ProtopopovaChristian E W Steinberg
Jun 19, 2007·Ecotoxicology and Environmental Safety·Sheku Kamara, Stephan Pflugmacher
Dec 1, 2012·Journal of Phycology·Yvonne Pörs, Christian E W Steinberg
Feb 8, 2006·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·M A Timofeyev
Jun 4, 2016·Ecotoxicology·Karen Adriana Novoa-LunaLeobardo Manuel Gómez-Oliván
Nov 3, 2011·Environmental Science & Technology·Peng Lin, Jian Zhen Yu
Apr 3, 2008·Environmental Science and Pollution Research International·Christian E W SteinbergRalph Menzel
Dec 2, 2020·Environmental Pollution·Adrian C LoveAlex T Ford
Aug 18, 2006·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·M A Timofeyev, C E W Steinberg
Oct 9, 2007·Ecotoxicology and Environmental Safety·M A TimofeyevA V Kolesnichenko

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