Specific characteristics of urethral strictures in a developing country (Brazil)

World Journal of Urology
R H AstolfiJulio J Geminiani

Abstract

Evaluate the main etiologies and clinical characteristics of male urethral stricture disease (USD) in Brazil. This multicentric study was performed using retrospective data collected from six Brazilian referral centers of urethral reconstruction. The database comprised data from 899 patients with USD who had undergone surgical treatment from 2008 to 2018. Age, stricture site and primary stricture etiology were identified for each patient. The mean age was 52.13 ± 16.9 years. The most common etiology was iatrogenic (43.4%), followed by idiopathic (21.7%), trauma (21.5%) and inflammatory (13.7%). Of the iatrogenic causes, 59% were secondary to urethral instrumentation (60% by urethral catheterization and 40% by transurethral procedures), 24.8% by other procedures (prostatectomy, radiotherapy, postectomy) and 16.2% by failed hypospadia repairs. Pelvic fracture urethral distraction injuries were responsible for most of the trauma-related strictures (62.7%). When stratified by age, the most common stricture etiology was trauma in the 0-39 years old group (42.8%), idiopathic in the 40-59 years old group (32.4%) and iatrogenic in patients over 60 years old (68%). In regard to the stricture site, 80% presented with an anterior urethral...Continue Reading

References

Mar 1, 1977·The Journal of Urology·R C Casselman, J F Schillinger
Jan 1, 1984·Scandinavian Journal of Urology and Nephrology·M RuutuC G Standertskjöld-Nordenstam
Aug 1, 1993·British Journal of Urology·L S Baskin, J W McAninch
Jul 1, 1996·The Journal of Urology·V Pansadoro, P Emiliozzi
Sep 28, 1998·European Urology·W Abu-ArafehA Farkas
Sep 6, 2000·BJU International·I DepasqualeA Bracka
Aug 13, 2003·The Journal of Urology·Thomas M KesslerMargit Fisch
May 26, 2005·Urology·Ann S FentonCarlos R Garcia
Apr 18, 2007·The Journal of Urology·Richard A SantucciMatthew Wise
Feb 5, 2008·European Urology·Guido BarbagliMassimo Lazzeri
Apr 22, 2008·The Journal of Urology·Carol KashefiJ Kellogg Parsons
Aug 22, 2008·European Urology·Daniela E Andrich, Anthony R Mundy
Jul 21, 2009·The Journal of Urology·Nicolaas LumenWillem Oosterlinck
Oct 5, 2010·Dermatologic Clinics·Ruth Murphy
Jul 16, 2011·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Rajkumar MathurSudarshan Odiya
Nov 17, 2012·Urology·Enzo PalminteriLuca Carmignani
Dec 21, 2012·BJU International·Daniel M SteinChris M Gonzalez
Mar 5, 2016·Indian Journal of Urology : IJU : Journal of the Urological Society of India·Thomas G Smith

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.