PMID: 6982792Sep 1, 1982Paper

Specific IgA and IgE in childhood asthma, eczema and food allergy

Clinical Allergy
B TaylorJ Abbott

Abstract

Allergen-specific IgA and IgE antibodies were compared in 250 children with asthma (Dermatophagoides pteronyssinus, rye grass pollen), in eighty-six children with eczema (whole egg, cow's milk) and in two groups of children with egg and cow's milk allergy. In each of the conditions investigated, food allergy, asthma and eczema increasing atopy was associated with increasing specific IgE levels to relevant allergens. There was no association of high IgE antibody levels with low IgA antibody levels in any of the conditions or allergens studied. There was, however, a tendency for subjects with more severe asthma to have high IgA levels with high IgE levels. IgA deficiency does not appear to be associated with atopic conditions of childhood.

References

Feb 12, 1977·Lancet·D J MatthewM W Turner
Jul 1, 1976·Clinical Allergy·J F SoothillB Taylor
Jul 1, 1976·Clinical Allergy·H S Kaufman, O L Frick
Oct 1, 1975·The Journal of Allergy and Clinical Immunology·H A OrgelW Wallace
Nov 21, 1970·Lancet·H S Kaufman, J R Hobbs
Jul 21, 1973·Lancet·B TaylorJ F Soothill
Jun 1, 1973·The Journal of Allergy and Clinical Immunology·J SalvaggioM Sly
Jan 1, 1974·Annals of the New York Academy of Sciences·G Taylor
Apr 1, 1973·The Journal of Allergy and Clinical Immunology·K S TseC E Arbesman
Mar 11, 1971·The New England Journal of Medicine·D P Schwartz, R H Buckley
Aug 1, 1980·Archives of Disease in Childhood·R P Ford, D M Fergusson

❮ Previous
Next ❯

Citations

May 12, 2010·Archivum Immunologiae Et Therapiae Experimentalis·Konstantinos SamitasApostolos Bossios
Mar 1, 1993·Cancer Causes & Control : CCC·L J HerrintonR S Greenberg
Jan 1, 1987·Scandinavian Journal of Infectious Diseases. Supplementum·H Schønheyder

❮ Previous
Next ❯

Related Concepts

Related Feeds

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Antibody Specificity

Antibodies produced by B cells are highly specific for antigen as a result of random gene recombination and somatic hypermutation and affinity maturation. As the main effector of the humoral immune system, antibodies can neutralize foreign cells. Find the latest research on antibody specificity here.

Allergies & Environmental Factors

Environmental factors are strongly associated with the prevalence of allergies and are an increasing health concern worldwide. Discover the latest research on Allergies and Environmental Factors here.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.