Specific psychological and behavioral symptoms of depression in patients with dementia

International Journal of Geriatric Psychiatry
Annie Prado-JeanJean Pierre Clément

Abstract

Behavioral and psychological symptoms in dementia (BPSD) are very common, with 90% of patients experiencing at least one during the course of the disease. One-third of persons with dementia have depressive symptoms, and concomitant BPSD are very likely. This study aimed to characterize the psychological and behavioral manifestations of depression in patients with dementia. We recruited patients with dementia from several nursing homes in the Limousin region of France. Depression was as diagnosed by the Cornell Scale for Depression in Dementia (CSDD) with a cut-off of 7, and BPSD were assessed using the Neuropsychiatric Inventory (NPI). Of 319 patients with dementia, 42.9% (n =137) were depressed and 75.9% (n = 242) had BPSD. All BPSD were significantly (p < 0.0001) more prevalent among depressed patients, but no significant differences were observed according to sex and age. The NPI showed that the most common additional symptoms in depressed patients were agitation (43.2%), anxiety (42.3%) and irritability (40.1%). Four NPI-based factors were indentified (63.9% of the common variance): factor 1 (disinhibition, irritability, agitation, anxiety), factor 2 (sleep disturbance, aberrant motor behavior, apathy), factor 3 (elation, h...Continue Reading

References

Nov 1, 1975·Journal of Psychiatric Research·M F FolsteinP R McHugh
Dec 1, 1990·The British Journal of Psychiatry : the Journal of Mental Science·A L Nyth, C G Gottfries
Jul 1, 1990·The British Journal of Psychiatry : the Journal of Mental Science·A BurnsR Levy
Feb 1, 1988·Biological Psychiatry·G S AlexopoulosC A Shamoian
Dec 23, 1998·Archives of General Psychiatry·S S BassukD Wypij
Apr 28, 2000·The American Journal of Psychiatry·C G LyketsosJ C Breitner
Mar 10, 2001·International Journal of Geriatric Psychiatry·A S MenonJ Magaziner
May 29, 2001·International Journal of Geriatric Psychiatry·H BrodatyD Lie
Jul 28, 2001·International Psychogeriatrics·P V Rabins
May 7, 2002·The Australian and New Zealand Journal of Psychiatry·A F Jorm
Aug 17, 2002·Biological Psychiatry·Constantine G Lyketsos, Jason Olin
Sep 24, 2002·JAMA : the Journal of the American Medical Association·Constantine G LyketsosSteven DeKosky
Dec 28, 2002·American Journal of Alzheimer's Disease and Other Dementias·Rita MorettiAntonio Bava
Mar 19, 2003·Journal of Geriatric Psychiatry and Neurology·Oscar HeerenJay Magaziner
Jan 9, 2004·La Revue de médecine interne·C ArbusB Vellas
Jan 13, 2004·International Journal of Geriatric Psychiatry·Martin SteinbergJohn C S Breitner
Feb 6, 2004·International Journal of Geriatric Psychiatry·Martin SteinbergConstantine G Lyketsos
Feb 3, 2005·JAMA : the Journal of the American Medical Association·Kaycee M SinkKristine Yaffe
May 28, 2005·International Journal of Geriatric Psychiatry·Pauline AaltenFrans R J Verhey
Oct 20, 2005·JAMA : the Journal of the American Medical Association·Lon S SchneiderPhilip Insel
Nov 3, 2005·The American Journal of Psychiatry·Sergio E StarksteinRobert G Robinson
Dec 1, 2006·International Journal of Geriatric Psychiatry·Sytse U ZuidemaRaymond T C M Koopmans
Sep 12, 2007·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Bruce G PollockKimberly A Huber
Sep 28, 2007·Archives of Gerontology and Geriatrics·Secundino López-PousaImma Pericot-Nierga
May 21, 2008·International Journal of Geriatric Psychiatry·Giuseppe BellelliMarco Trabucchi
Sep 4, 2008·International Journal of Geriatric Psychiatry·Anna-Katharina TheisonStefan G Schröder
Oct 18, 2008·International Review of Psychiatry·Clive BallardSusanne Sorensen
Jan 27, 2009·Medical Care·Joseph E GauglerJean F Wyman
Mar 13, 2009·International Journal of Geriatric Psychiatry·Sytse U ZuidemaRaymond T C M Koopmans

❮ Previous
Next ❯

Citations

May 18, 2012·International Psychogeriatrics·Tomislav MajićMichael A Rapp
Aug 14, 2012·Neuropsychiatric Disease and Treatment·Francesco MargariMaria Giuseppina Petruzzelli
May 27, 2015·International Journal of Older People Nursing·Barbara Resnick, Elizabeth Galik
Mar 20, 2012·International Journal of Nursing Studies·Alida H P M de RooijJos M G A Schols
Apr 1, 2011·Journal of the American Medical Directors Association·Ladislav Volicer
Aug 17, 2011·International Journal of Geriatric Psychiatry·Lisa L BoyleYeates Conwell
Dec 21, 2012·International Journal of Geriatric Psychiatry·Stefan Van der MusseleSebastiaan Engelborghs
Jan 12, 2012·Geriatrics & Gerontology International·Ayako EdahiroGen-yuki Yamane
Dec 3, 2011·International Journal of Geriatric Psychiatry·Ruslan LeontjevasRaymond T C M Koopmans
Mar 29, 2014·International Journal of Geriatric Psychiatry·Rianne M van der LindeCarol Brayne
Apr 17, 2015·International Psychogeriatrics·Brian M Draper
May 15, 2012·Journal of the American Medical Directors Association·Ladislav Volicer
Oct 19, 2016·International Journal of Geriatric Psychiatry·Alexandra S CreightonDavid W Kissane
Feb 26, 2016·Journal of Applied Gerontology : the Official Journal of the Southern Gerontological Society·Elaine M BaileyForrest Scogin
Jan 28, 2014·International Journal of Palliative Nursing·Sandra A ZwijsenMartin Smalbrugge
Apr 15, 2017·Neurology. Clinical Practice·Zahra Goodarzi, Zahinoor Ismail
Aug 25, 2015·World Journal of Clinical Cases·Miquel Baquero, Nuria Martín
Jul 1, 2020·Dementia and Neurocognitive Disorders·YoungSoon YangYong Tae Kwak
Sep 16, 2013·The Medical Journal of Australia·Eleanor M Curran, Samantha Loi
Apr 15, 2021·Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring·Valérie GodefroyRaffaella Migliaccio

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Alzheimer Disease and Associated Disorders
R C Abrams, G S Alexopoulos
Annals of Internal Medicine
David Margolius, Thomas Bodenheimer
International Journal of Geriatric Psychiatry
Sytse U ZuidemaRaymond T C M Koopmans
© 2021 Meta ULC. All rights reserved