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Specific transformations at the N-terminal region of phospholipase A2

Biochemistry

Dec 16, 1975

A J Slotboom, G H de Haas

PMID: 1238112

Abstract

Treatment of porcine pancreatic prophospholipase A2 with methyl acetimidate converted all lysine residues into epsilon-acetimidolysine residues. Enzymatically active epsilon-amidinated phospholipase A2 (AMPA) was obtained from the epsilon-amidinated zymogen by limited tryptic proteolysi...read more

Mentioned in this Paper

Phospholipase A2, human
CD7 wt Allele
Methyl acetimidate
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
Structure-Activity Relationship
Amino Acids, I.V. solution additive
Acetamides
Prophospholipase A2
Lysine
Trypsin
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Specific transformations at the N-terminal region of phospholipase A2

Biochemistry

Dec 16, 1975

A J Slotboom, G H de Haas

PMID: 1238112

DOI:

Abstract

Treatment of porcine pancreatic prophospholipase A2 with methyl acetimidate converted all lysine residues into epsilon-acetimidolysine residues. Enzymatically active epsilon-amidinated phospholipase A2 (AMPA) was obtained from the epsilon-amidinated zymogen by limited tryptic proteolysi...read more

Mentioned in this Paper

Phospholipase A2, human
CD7 wt Allele
Methyl acetimidate
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
Structure-Activity Relationship
Amino Acids, I.V. solution additive
Acetamides
Prophospholipase A2
Lysine
Trypsin

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