Specific types of bladder cancer

Der Pathologe
Simone BertzN T Gaisa

Abstract

Bladder cancer shows rare variants and special subtypes with diverse prognostic importance and therefore may necessitate different therapeutic approaches. For pathologists it is important to histologically diagnose and specify such variants. Nested variants of urothelial carcinoma with inconspicuous, well-formed tumor cell nests present with an aggressive course. The plasmacytoid variant, which morphologically resembles plasma cells is associated with a shorter survival time and a high frequency of peritoneal metastasis. Micropapillary urothelial carcinoma with small papillary tumor cell islands within artificial tissue retraction spaces and frequent lymphovascular invasion also has a poor prognosis. Other important rare differential variants listed in the World Health Organization (WHO) classification are microcystic, lymphoepithelioma-like, sarcomatoid, giant cell and undifferentiated urothelial carcinomas. Additionally, there are three special types of bladder cancer: squamous cell carcinoma, adenocarcinoma and small cell neuroendocrine carcinoma of the bladder. These tumors are characterized by pure squamous cell or glandular differentiation and are sometimes less responsive to adjuvant (chemo)therapy. Small cell carcinoma ...Continue Reading

References

Dec 1, 1992·Journal of Korean Medical Science·J H ChoI Lee
Nov 1, 1991·American Journal of Clinical Pathology·R H Young, L R Zukerberg
Jan 1, 1989·Virchows Archiv. A, Pathological Anatomy and Histopathology·J E MartinS I Baithun
Jan 1, 1984·The Journal of Urology·C A SheldonE E Fraley
May 20, 1999·The Journal of Urology·S L JohanssonS Holmäng
Jul 27, 2001·Virchows Archiv : an International Journal of Pathology·A Lopez-BeltránR Montironi
Dec 19, 2003·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Oscar LinVictor E Reuter
Jun 1, 2006·International Journal of Urology : Official Journal of the Japanese Urological Association·Takurou KohnoToshitugu Oka
Aug 3, 2006·Journal of Clinical Pathology·Antonio Lopez-BeltranRodolfo Montironi
Sep 5, 2006·Human Pathology·Antonio Lopez-Beltran, Liang Cheng
Apr 2, 2008·The American Journal of Surgical Pathology·Jae Y RoAlberto G Ayala
Mar 20, 2009·Human Pathology·Antonio Lopez-BeltranLiang Cheng
Dec 8, 2010·Virchows Archiv : an International Journal of Pathology·Nadine T GaisaRuth Knuechel
Jan 17, 2012·The Journal of Urology·Roberto Rafael Ricardo-GonzalezJesse K McKenney
Jun 1, 2012·Archives of Pathology & Laboratory Medicine·Elizabeth McQuittyAlberto G Ayala
Nov 20, 2012·The Journal of Urology·Farshid DayyaniArlene O Siefker-Radtke
Dec 11, 2013·Histopathology·Antonio Lopez BeltranLiang Cheng
Jun 1, 2014·Virchows Archiv : an International Journal of Pathology·Antonio Lopez BeltranEva Comperat
Aug 15, 2014·The American Journal of Surgical Pathology·Minghao ZhongJonathan I Epstein
Mar 27, 2015·Virchows Archiv : an International Journal of Pathology·J TschuiA Fleischmann
May 6, 2015·Experimental Hematology & Oncology·Xiaoyong ZhengMinghao Zhong

❮ Previous
Next ❯

Citations

Nov 11, 2019·Der Pathologe·H Reis, T Szarvas
May 11, 2019·Der Pathologe·H ReisV Grünwald

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atherosclerosis Disease Progression

Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.

Bladder Carcinoma In Situ

Bladder Carcinoma In Situ is a superficial bladder cancer that occurs on the surface layer of the bladder. Discover the latest research on this precancerous condition in this feed.

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.