Specification of polarity of teloblastogenesis in the oligochaete annelid Tubifex: cellular basis for bilateral symmetry in the ectoderm

Developmental Biology
Ayaki NakamotoTakashi Shimizu

Abstract

Ectodermal teloblastogenesis in the oligochaete annelid Tubifex is a spatiotemporally regulated process that gives rise to four bilateral pairs of ectoteloblasts (N, O, P, and Q) that assume distinct fates. Ectoteloblasts on either side of the embryo arise from an invariable sequence of asymmetric cell divisions of a proteloblast, NOPQ, which occur with a defined orientation with respect to the embryonic axes: the N teloblast is generated first and located ventralmost, and the Q teloblast, which is generated next, is located dorsalmost; finally, the O and P teloblasts are generated by almost equal division of their precursor cell, OP. Polarity of teloblastogenesis on one side of the embryo is a mirror image of the other; this mirror symmetry of ectoteloblasts about the embryo's midline gives rise to the bilaterally symmetric organization of the ectoderm. In this study, we examined whether cellular interactions are involved in specification of polarity of asymmetric cell divisions in NOPQ cells. A set of cell transplantation experiments demonstrated that NOPQ cells are initially uncommitted in terms of division pattern and cell fates: If a left NOPQ cell is transplanted to the right side of a host embryo, it exhibits a polarity ...Continue Reading

References

Jun 1, 1997·Development, Growth & Differentiation·H Takahashi, T Shimizu
Jun 25, 1998·Development, Growth & Differentiation·T ShimizuH Takahashi
Jan 26, 2000·Development, Growth & Differentiation·A GotoT Shimizu
Dec 5, 2000·Current Biology : CB·B Goldstein

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Citations

Jun 19, 2017·Development Genes and Evolution·Momoe Aoki, Takashi Shimizu
Feb 15, 2019·Journal of Morphology·Noriyuki YoshidaTakashi Shimizu

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