Specificity and editing by apoptosis of virus-induced cytotoxic T lymphocytes

Current Opinion in Immunology
L K Selin, R M Welsh

Abstract

Recent studies have defined an immunological network by which the acute cytotoxic T-lymphocyte response to viral infection modulates or is modulated by the antigen load and by crossreactive memory T cells. Down regulation of the acute CTL response can be associated with either antigen-dependent or antigen-independent apoptosis, and the host enters a state of immune deficiency as these T cells become sensitized to apoptotic mechanisms.

References

Nov 1, 1992·The Journal of Cell Biology·Y GavrieliS A Ben-Sasson
Jun 1, 1991·Immunology Today·A N AkbarG Janossy
Jun 1, 1990·Immunology Today·P C Beverley
Nov 1, 1986·Reviews of Infectious Diseases·B T Rouse, D W Horohov
Dec 1, 1994·International Archives of Allergy and Immunology·A N AkbarG Janossy
Apr 1, 1994·The Journal of Experimental Medicine·D F Tough, J Sprent
Jun 1, 1994·The Journal of Experimental Medicine·L K SelinR M Welsh
Jan 18, 1994·Proceedings of the National Academy of Sciences of the United States of America·P AicheleH Pircher
Feb 1, 1993·The Journal of Experimental Medicine·S R CardingP C Doherty

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Citations

Jun 1, 1997·Current Opinion in Immunology·J Sprent
Nov 1, 1995·Trends in Microbiology·B BlacklawsI McConnell
Mar 11, 1998·Proceedings. Biological Sciences·D WodarzM A Nowak
Apr 1, 1996·Immunological Reviews·P C DohertyR A Tripp
Apr 1, 1996·Immunological Reviews·D F Tough, J Sprent
Jan 1, 1997·Annual Review of Immunology·A J McMichael, R E Phillips
Dec 29, 2007·The Journal of Pathology·C M Filippi, M G von Herrath
Feb 19, 2010·Journal of Medical Virology·Jinsheng WenLifang Jiang
Apr 25, 2012·PLoS Neglected Tropical Diseases·Luana de BorbaClaudia N Duarte Dos Santos
Feb 13, 2001·The Journal of Immunology : Official Journal of the American Association of Immunologists·S M VargaR M Welsh
May 29, 2002·Cell Death and Differentiation·Y ZhangI N Mbawuike
Mar 9, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Tonya J RobertsRandy R Brutkiewicz
Dec 12, 2001·The Journal of Immunology : Official Journal of the American Association of Immunologists·D J TophamP C Doherty
May 4, 2006·The Journal of Immunology : Official Journal of the American Association of Immunologists·Emma L TurnbullPersephone Borrow
Jan 12, 1996·Science·R M Zinkernagel

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Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis