Sharing of weak signals of positive selection across the genome

BioRxiv : the Preprint Server for Biology
Nathan Scott Harris, A. R. Rogers

Abstract

Selection in humans often leaves subtle signatures at individual loci. Few studies have measured the extent to which these signals are shared among human populations. Here a new method is developed to compare weak signals of selection in aggregate across the genome using the 1000 Genomes Phase 3 Data. Results presented here show that selection producing weak selection serves to increase population differences around coding areas of the genome.

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