Spectral analysis of arterial pressure variability during induction of propofol anesthesia

Anesthesia and Analgesia
H WangP W Lui

Abstract

We studied the effect of continuous infusion of propofol on spectral components in systemic arterial pressure (SAP) signals in 35 consenting patients undergoing abdominal surgery. Anesthesia was induced with intravenous bolus administration of propofol (2.0 mg/kg), followed by infusion at either 5 mg.kg-1.h-1 (Group 1, n = 18) or 10 mg.kg-1.h-1 (Group 2, n = 17). Tracheal intubation was facilitated by administration of vecuronium (0.1 mg/kg). The SAP signal was subjected to off-line spectral analysis to obtain changes in power of the very low frequency (VLF; 0.00-0.08 Hz), low frequency (LF; 0.08-0.15 Hz), high frequency (0.15-0.25 Hz); and very high frequency (VHF; 0.80-1.60 Hz) components. Venous blood for the measurement of plasma concentration of propofol was collected at 5 min before bolus injection of propofol; at 5, 10, and 15 min after infusion of propofol; and immediately after endotracheal intubation. Infusion of propofol significantly decreased the total power of SAP spectrum in both groups, especially the VLF, LF, and VHF components at all intervals except postintubation. Immediately after tracheal intubation, patients in Group 1 showed a significant increase in mean arterial pressure when compared with those in Gro...Continue Reading

References

Jul 1, 1992·Journal of Clinical Anesthesia·T W LatsonJ M Lipton
Apr 1, 1992·British Journal of Anaesthesia·D C GalletlyB J Robinson
Mar 1, 1991·The American Journal of Physiology·Y Inoue, N Sperelakis
Aug 1, 1991·Circulation·A MallianiS Cerutti
Jul 1, 1991·Journal of the Autonomic Nervous System·M PaganiA Malliani
Jun 1, 1990·Journal of the Autonomic Nervous System·N JapundzicJ L Elghozi
Nov 1, 1989·Clinical Pharmacokinetics·J Kanto, E Gepts
Jan 1, 1988·British Journal of Anaesthesia·M A ClaeysF Camu
Feb 1, 1988·British Journal of Anaesthesia·T KirkpatrickW S Nimmo
May 1, 1986·Anaesthesia·J W DundeeC C Patterson
Sep 1, 1987·British Journal of Anaesthesia·I D CockshottM White
Feb 1, 1994·British Journal of Anaesthesia·D C GalletlyT Corfiatis
Feb 1, 1994·British Journal of Anaesthesia·D C GalletlyT Corfiatis
Nov 1, 1993·Neuroscience·R C Van Sluyters
Jun 1, 1993·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·S SegaT Kiauta

❮ Previous
Next ❯

Citations

Sep 18, 1999·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Y FujiwaraY Shimada
Jun 30, 2011·The Journal of Physiological Sciences : JPS·Takahiko YoshimotoTakao Kumazawa
Jan 5, 1999·Journal of Clinical Anesthesia·J E TetzlaffA Schubert
Jul 2, 2003·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Daniel L ToweillBrahm Goldstein
Apr 18, 2003·Acta Anaesthesiologica Scandinavica·J UllmanM Rundgren
Jan 8, 2021·European Journal of Clinical Pharmacology·Gustavo H Oliveira-PaulaRiccardo Lacchini

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.