PMID: 9648968Jul 2, 1998Paper

Spectral analysis of wakefulness and REM sleep EEG in patients with sleep apnoea syndrome

The European Respiratory Journal
F MorissonJacques Montplaisir

Abstract

Neuropsychological investigations of patients with obstructive sleep apnoea syndrome (OSAS) have shown impairments in such basic functions as memory, attention and executive control. Since executive functions are known to be dependent on the integrity of the frontal lobe, it was hypothesized that OSAS may be associated with hypoxaemic frontal lobe dysfunction. To test this hypothesis, 21 apnoeic patients and 10 normal controls were studied with quantitative electroencephalographic (EEG) methods during rapid eye movement (REM) sleep, when most apnoeic events occur and during wakefulness. In apnoeic patients, EEG slowing in REM sleep was observed over frontal, central and parietal regions, while EEG slowing during wakefulness was observed over all cortical regions examined. A positive correlation was found between EEG slowing during wakefulness and oxygen desaturation during the night. Contrary to the hypothesis, these electroencephalographic changes were not localized only to the frontal region. This result may explain the wide range of neuropsychological deficits noted in patients with obstructive sleep apnoea syndrome, in addition to their poor performance in tasks of executive functioning.

Citations

Feb 23, 2010·Sleep & Breathing = Schlaf & Atmung·Athanasios G XiromeritisNikiforos V Angelopoulos
Feb 26, 2013·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Claudio Del PercioClaudio Babiloni
Sep 19, 2012·BMC Neuroscience·Suzana V SchönwaldGünther J L Gerhardt
Aug 1, 2013·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Diego Z CarvalhoSuzana V Schönwald
Jul 30, 2014·Pathologie-biologie·K GagnonN Gosselin
May 31, 2014·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·David WangRonald R Grunstein
Oct 21, 2015·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Andrew VakulinRonald Grunstein
Jul 14, 2012·Journal of Psychosomatic Research·Sang Don LeeIn-Young Yoon
May 18, 2007·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Annie MathieuJacques Montplaisir
Mar 3, 2009·Journal of Sleep Research·Khalid YaouhiBéatrice Desgranges
Apr 9, 2013·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Angela L D'RozarioRonald R Grunstein
Apr 19, 2015·The Lancet. Respiratory Medicine·Ivana RosenzweigMary J Morrell
Aug 24, 2016·Australasian Physical & Engineering Sciences in Medicine·N SriraamUma Maheshwari
Mar 2, 2019·Journal of Sleep Research·Joseph J Y PoonAngela L D'Rozario
Mar 8, 2019·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·Aljohara S AlmeneessierAhmed S BaHammam
Sep 5, 2014·Current Opinion in Pulmonary Medicine·Ivana RosenzweigMary J Morrell
Jan 19, 2017·Reviews in the Neurosciences·Szilvia PuskásMária Tünde Magyar
Jul 24, 2021·Clinical Psychopharmacology and Neuroscience : the Official Scientific Journal of the Korean College of Neuropsychopharmacology·Jae Myeong KangSeung-Gul Kang
Jul 8, 2021·Pediatric Research·Christy R SibaraniRosemary S C Horne

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.