Spectral decomposition of susceptibility artifacts for spectral-spatial radiofrequency pulse design.

Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
Cungeng YangV Andrew Stenger

Abstract

Susceptibility induced signal loss is a limitation in gradient echo functional MRI. The through-plane artifact in axial slices is particularly problematic due to the inferior position of air cavities in the brain. Spectral-spatial radiofrequency pulses have recently been shown to reduce signal loss in a single excitation. The pulses were successfully demonstrated assuming a linear relationship between susceptibility gradient and frequency, however, the exact frequency and spatial distribution of the susceptibility gradient in the brain is unknown. We present a spiral spectroscopic imaging sequence with a time-shifted radiofrequency pulse that can spectrally decompose the through-plane susceptibility gradient for spectral-spatial radiofrequency pulse design. Maps of the through-plane susceptibility gradient as a function of frequency were generated for the human brain at 3T. We found that the linear relationship holds well for the whole brain with an optimal slope of -1.0 μT/m/Hz.

References

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Oct 17, 2006·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Chun-Yu YipDouglas C Noll
Jan 24, 2009·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Weiran DengV Andrew Stenger
Mar 10, 2009·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Chun-Yu YipDouglas C Noll
Apr 8, 2009·NeuroImage·Benedikt A Poser, David G Norris
Jan 26, 2011·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Cungeng YangV Andrew Stenger

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Citations

Dec 18, 2013·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Robert J AndersonV Andrew Stenger
Oct 8, 2014·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Rainer SchneiderJosef Pfeuffer
Oct 8, 2015·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Bastien GuérinLawrence L Wald

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