Spectral-domain optical coherence tomography angiography of choroidal neovascularization

Ophthalmology
Talisa E de CarloNadia K Waheed

Abstract

To describe the characteristics as well as the sensitivity and specificity of detection of choroidal neovascularization (CNV) on optical coherence tomography angiography (OCTA) using spectral-domain optical coherence tomography. Observational, retrospective study. Seventy-two eyes of 61 subjects (48 eyes of 43 subjects with CNV, 24 eyes of 18 subjects without CNV). Patients imaged using the prototype AngioVue OCTA system (Optovue, Inc, Fremont, CA) between August 2014 and October 2014 at New England Eye Center were assessed. Patients in whom CNV was identified on OCTA were evaluated to define characteristics of CNV on OCTA: size using greatest linear dimension (small, <1 mm; medium, 1-2 mm; large, >2 mm), appearance (well-circumscribed, poorly circumscribed), and presence of subretinal and intraretinal fluid. Concurrently, an overlapping second cohort of patients who underwent same-day OCTA and fluorescein angiography (FA) for suspected CNV was evaluated to estimate sensitivity and specificity of OCTA in detecting CNV using FA as ground truth. Choroidal neovascularization appearance, CNV size, and presence of subretinal and intraretinal fluid. In 48 eyes, CNV was visualized on OCTA. Thirty-one eyes had CNV associated with neova...Continue Reading

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Citations

Feb 16, 2016·Ophthalmic Surgery, Lasers & Imaging Retina·Talisa E de CarloNadia K Waheed
Feb 16, 2016·Ophthalmic Surgery, Lasers & Imaging Retina·Talisa E de CarloElias Reichel
Feb 16, 2016·Ophthalmic Surgery, Lasers & Imaging Retina·Talisa E de CarloNadia K Waheed
Oct 21, 2015·Progress in Retinal and Eye Research·Daniela FerraraJay S Duker
Jan 6, 2016·Ophthalmic Surgery, Lasers & Imaging Retina·Jason T SzelogJay S Duker
Dec 24, 2015·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·P P FangF G Holz
Dec 2, 2015·American Journal of Ophthalmology·João Nobre CardosoAdnan Tufail
Oct 13, 2015·Retina·Alexandra MiereEric H Souied
Nov 26, 2015·Ophthalmic Surgery, Lasers & Imaging Retina·Alexander H de Castro-AbegerCaroline R Baumal
Dec 8, 2015·Clinical & Experimental Ophthalmology·Eduardo A NovaisNadia K Waheed
Dec 1, 2015·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Ju Young KimYong Sung You
Mar 15, 2016·American Journal of Ophthalmology·Manabu MiyataNagahisa Yoshimura
Oct 28, 2015·BioMed Research International·Alex D PechauerYali Jia
May 20, 2016·Journal of Ophthalmic & Vision Research·K V Chalam, Kumar Sambhav
Apr 27, 2016·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Jessica I W Morgan
Aug 28, 2015·The British Journal of Ophthalmology·Marcus AngMark R Wilkins
May 14, 2016·Expert Review of Medical Devices·Rupesh AgrawalAniruddha Agarwal
Sep 16, 2016·Ophthalmic Surgery, Lasers & Imaging Retina·Eduardo A NovaisJay S Duker
Oct 21, 2016·Ophthalmic Surgery, Lasers & Imaging Retina·Ricardo Noguera LouzadaCaroline R Baumal
Dec 16, 2016·Ophthalmic Surgery, Lasers & Imaging Retina·Shintaro NakaoKoh-Hei Sonoda
Dec 4, 2016·The British Journal of Ophthalmology·Mehrdad MalihiSteven T Bailey
Jan 30, 2016·The British Journal of Ophthalmology·Marcus AngMark R Wilkins

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