Spectral domain optical coherence tomography findings of patients with ankylosing spondylitis.

International Ophthalmology
Ali KalCaner Öztürk

Abstract

The aim of this study is to evaluate the possible effects of (ankylosing spondylitis) AS on choroidal thickness (CT) and other retinal layers using spectral domain optical coherence tomography (SD-OCT). This cross-sectional study group comprised 41 AS patients and age and sex-matched 46 control subjects. None of our patients had active anterior uveitis during the measurements. We evaluated and compared CT, retinal nerve fiber layer (RNFL) thickness, ganglion cell complex (GCC) thickness, focal loss volume (FLV) and global loss volume (GLV) of the participants. The CT of the patients at 1500 µm (286.20 µm ± 65.81), 1000 µm (309.55 µm ± 85.33) nasally to the fovea and subfoveal layer (339.93 µm ± 69.93) were thicker than in controls (p = 0.007, p = 0.037, p = 0.008). Except nasal layer, all RNFL layers were significantly thinner than controls (p < 0.001). GCC and macular thickness were also thinner than controls (p < 0.001). In conclusion, present findings may suggest that the AS disease may affect the choroidal, RNFL and GCC thickness by disease's own inflammatory effect, independently from the uveitis history.

References

Oct 3, 1999·Experimental Eye Research·J W Kiel
Sep 10, 2009·Investigative Ophthalmology & Visual Science·Hideko SawadaHaruki Abe
Feb 8, 2011·Autoimmunity Reviews·Anthoula ChatzikyriakidouAlexandros A Drosos
Dec 15, 2011·Investigative Ophthalmology & Visual Science·Colin S TanSriniVas R Sadda
Mar 20, 2012·Best Practice & Research. Clinical Rheumatology·Michael Ehrenfeld
Sep 27, 2012·Ophthalmology·Wen Bin WeiQi Sheng You
Dec 21, 2012·Ocular Immunology and Inflammation·Tanya KaraconjiPeter McCluskey
Mar 6, 2013·Journal of Glaucoma·James D DalglieshPaul Mitchell
Jul 31, 2013·Ocular Immunology and Inflammation·Erol CoskunA Mesut Onat
Jul 6, 2014·Ocular Immunology and Inflammation·Mehmet KolaAhmet Ayar
Sep 27, 2014·Current Opinion in Ophthalmology·Sophia L Zagora, Peter McCluskey
Oct 16, 2015·Arquivos brasileiros de oftalmologia·Ibrahim Koral OnalMehmet Arhan
Mar 10, 2016·International Ophthalmology·Fatih Mehmet Türkcüİhsan Çaça
Jul 19, 2016·Retina·Cagatay KaracaGalip Ertugrul Mirza
Oct 5, 2018·Ocular Immunology and Inflammation·Mirinae KimYoung-Hoon Park

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.