Spectral entropy monitoring for adults and children undergoing general anaesthesia

The Cochrane Database of Systematic Reviews
Anjolie ChhabraSaloni Paranjape


Anaesthetic drugs during general anaesthesia are titrated according to sympathetic or somatic responses to surgical stimuli. It is now possible to measure depth of anaesthesia using electroencephalography (EEG). Entropy, an EEG-based monitor can be used to assess the depth of anaesthesia using a strip of electrodes applied to the forehead, and this can guide intraoperative anaesthetic drug administration. The primary objective of this review was to assess the effectiveness of entropy monitoring in facilitating faster recovery from general anaesthesia. We also wanted to assess mortality at 24 hours, 30 days, and one year following general anaesthesia with entropy monitoring.The secondary objectives were to assess the effectiveness of the entropy monitor in: preventing postoperative recall of intraoperative events (awareness) following general anaesthesia; reducing the amount of anaesthetic drugs used; reducing cost of the anaesthetic as well as in reducing time to readiness to leave the postanaesthesia care unit (PACU). We searched the Cochrane Central Register of Controlled Trials (CENTRAL; 2014, Issue 10), MEDLINE via Ovid SP (1990 to September 2014) and EMBASE via Ovid SP (1990 to September 2014). We reran the search in CENTR...Continue Reading

Associated Clinical Trials


Jul 1, 1992·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·P Dion
Jun 1, 1970·British Journal of Anaesthesia·D D BriceJ E Utting
Nov 1, 1970·Anesthesia and Analgesia·J A Aldrete, D Kroulik
Apr 1, 1984·Anesthesia and Analgesia·C B CameronG A Gregory
Apr 1, 1994·Anesthesiology·J LermanS Yentis
Oct 6, 1997·Acta Anaesthesiologica Scandinavica·O NordströmR Sandin
Nov 20, 1998·Anesthesiology·N P DowdA N Sandler
Apr 16, 2002·Acta Anaesthesiologica Scandinavica·M Enlund, H G Hassan
Jul 12, 2002·Statistics in Medicine·Julian P T Higgins, Simon G Thompson
Sep 27, 2002·Anesthesiology Clinics of North America·Pete H SpitellieKaren B Domino
Sep 6, 2003·BMJ : British Medical Journal·Julian P T HigginsDouglas G Altman
Mar 5, 2004·Acta Anaesthesiologica Scandinavica·H Viertiö-OjaP Meriläinen
Dec 24, 2004·Anesthesia and Analgesia·Terri G MonkJeffrey C Sigl
Mar 31, 2006·Anesthesiology·Jaakko G M KlockarsTomi Taivainen
Jun 6, 2006·British Journal of Anaesthesia·J BruhnM M R F Struys
Nov 24, 2006·Anesthesia and Analgesia·Isabelle AiméMarc Fischler
Jan 10, 2008·Annales Françaises D'anesthèsie Et De Rèanimation·P RevironM Freysz
Feb 23, 2008·Anesthesia and Analgesia·Daryn H Moller, Ira J Rampil
May 24, 2008·BMJ : British Medical Journal·Gordon H GuyattUNKNOWN GRADE Working Group
Sep 24, 2008·Acta Anaesthesiologica Taiwanica : Official Journal of the Taiwan Society of Anesthesiologists·Shao-Chun WuAn-Kuo Chou
Jul 23, 2009·BMJ : British Medical Journal·David MoherUNKNOWN PRISMA Group
Oct 29, 2009·Anesthesia and Analgesia·Kate LeslieTimothy J McCulloch
Nov 17, 2009·Anesthesia and Analgesia·Kate LeslieMatthew T V Chan
Dec 1, 2009·Journal of Cardiothoracic and Vascular Anesthesia·Werner BauligUrs Schwarz
Feb 13, 2010·Acta Anaesthesiologica Scandinavica·S R ChoiC J Chung
Oct 6, 2011·Current Opinion in Anaesthesiology·Terri G Monk, B Craig Weldon
Apr 17, 2012·Journal of Cardiothoracic and Vascular Anesthesia·Ma JiahaiJiang Xiuliang
Jan 23, 2013·Anesthesiology·Tarek El HorJavad Bidgoli

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Nov 2, 2016·The Cochrane Database of Systematic Reviews·Anthony G MessinaNathan Leon Pace
May 4, 2017·Paediatric Drugs·Ramón Eizaga RebollarLuis M Torres Morera
Jun 3, 2021·Pharmaceuticals·Michał Jan StasiowskiPrzemysław Jałowiecki
Jan 13, 2021·Minerva anestesiologica·Simonetta TesoroJurgen C DE Graaff

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