PMID: 16526264Mar 11, 2006Paper

Spectrum of echocardiographic findings in patients with systemic sarcoidosis

Medicinski pregled
Milan PetrovićMarija Boricić

Abstract

Sarcoidosis is a granulomatous disease that may involve multiple organ systems. Cardiac sarcoidosis may be a primary or a secondary process. Clinical manifestations of cardiac sarcoidosis include impulse conduction disorders, various arrhythmias, symptoms and signs of heart failure and even sudden death. The aim of the present paper was to assess the possibilities for echocardiographic detection of pathological changes in the hearts of patients with diagnosed systemic sarcoidosis. The study group consisted of 31 patients with histological evidence of sarcoidosis obtained by biopsy of target organ (most frequently the lungs). There were 26 females and 5 males, aged from 38 to 74 years, mean age 53.67 +/- 9.48 years. The duration of sarcoidosis varied from 1 to 33 years, mean duration 6.56 years. All patients underwent Color Doppler echocardiographic examination with standard echocardiographic views. Increased left ventricular end-diastolic diameter was registered in 6/31 patients (19%), while end-systolic dimension was increased in 2 patients (6%). However, left ventricular dimensions were more increased in the group of patients with sarcoidosis lasting 4 years or longer. Majority of patients with sarcoidosis (27/31 or 86%) had ...Continue Reading

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