Spectrum of supraesophageal complications of gastroesophageal reflux disease

The American Journal of Medicine
W J Hogan

Abstract

There is a growing body of clinical and research evidence to support the role of gastroesophageal reflux in the etiology of certain disorders occurring in structures located above the body of the esophagus. These supraesophageal complications have only recently been identified but substantiation of the role of gastroesophageal reflux has been difficult and sometimes impossible with the technology currently available. This introductory article to the clinical issues involved in supraesophageal complications of GERD presents several index cases and asks far more questions than it gives answers about these patients. Clinical evidence supporting the role of GERD is discussed and the results of therapy reviewed. Education of the practicing physician to the role of supraesophageal complications of GERD is urged to help recognize the likelihood of such clinical conditions. There is a real need for additional clinical use and evaluation of multi site intraesophageal and pharyngeal pH probes in patients with suspected supraesophageal complications of GERD. More importantly, development of new techniques for measuring micro reflux events and sophisticated methods for determining the duration of acid exposure in tissues above the esophagu...Continue Reading

References

Jun 1, 1995·Annals of Internal Medicine·P L SchroederJ E Richter
Nov 1, 1994·Oral Surgery, Oral Medicine, and Oral Pathology·J H MeurmanE Klemetti
Sep 1, 1994·Journal of Clinical Gastroenterology·M A LaukkaA J Schei
Apr 1, 1996·The American Journal of Medicine·S M HardingL A Bradley
Sep 1, 1996·The American Journal of Gastroenterology·T T Schubert
Sep 25, 1996·JAMA : the Journal of the American Medical Association·P J Kahrilas
Nov 1, 1996·Postgraduate Medicine·W M Brady, C P Ogorek

❮ Previous
Next ❯

Citations

May 11, 2000·Disease-a-month : DM·W J Hogan, R Shaker
Aug 9, 2008·Digestive Diseases and Sciences·Kathryn A PetersonJohn C Fang
Nov 22, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·John A HermosElizabeth V Lawler
May 1, 2009·Expert Review of Clinical Pharmacology·Alex Mejia, Walter K Kraft
Apr 14, 2005·The Annals of Otology, Rhinology, and Laryngology·Clarence T SasakiRichard N Eisen
May 29, 2004·Current Opinion in Otolaryngology & Head and Neck Surgery·Rami E LutfiWilliam O Richards
Feb 18, 2006·Minerva gastroenterologica e dietologica·A J P M Smout
Sep 9, 2006·Medicine and Science in Sports and Exercise·Sheila Rodriguez-StanleyPhilip B Miner
Feb 1, 2019·Terapevticheskiĭ arkhiv·V N AbrosimovM V Solodun
Nov 19, 2003·European Journal of Gastroenterology & Hepatology·John N Groen, André J Smout
Feb 17, 2015·World Journal of Clinical Cases·Andrea CiorbaCarlo Vittorio Feo
Apr 1, 2001·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·T Ramadass, N Narayanan

❮ Previous
Next ❯

Related Concepts

Related Feeds

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.