PMID: 6976545Aug 1, 1981Paper

Specular microscopic and histologic observations in nonguttate corneal endothelial degeneration

Ophthalmology
R L AbbottW H Spencer

Abstract

Six phakic patients with unilateral corneal edema and clinically normal-appearing fellow eyes were examined with specular microscopy and found to have endothelial pleomorphism and reduced cell counts in the nonedematous cornea. None of these patients had any previous eye disease, trauma, inflammation, or surgery. Clinically unrecognized endothelial disease was proposed as a cause for the unilateral corneal edema and was verified by light and electron microscopic studies in five patients. These pathologic findings vary somewhat from those found in Fuchs' dystrophy and may represent either a variant or a form of endothelial cell degeneration of as yet undetermined etiology. Our studies suggest that this condition is not detectable in the nonedematous cornea by standard high magnification biomicroscopy and requires the use of the clinical specular microscope to confirm the diagnosis in suspected cases.

References

Aug 1, 1979·Archives of Ophthalmology·R L Abbott, R K Forster
Jun 1, 1978·Ophthalmology·E L ShawJ V Aquavella

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Citations

Jan 1, 1995·Eye·G O Naumann
Aug 1, 1990·Australian and New Zealand Journal of Ophthalmology·A M BrooksW E Gillies
Sep 1, 1993·Survey of Ophthalmology·A P AdamisR C Tripathi
Apr 9, 2015·Cornea·Jonathan H LassUNKNOWN Writing Committee for the Cornea Preservation Time Study Group
Apr 22, 2016·Cornea·Ali Bulent CankayaMerve Inanc
May 1, 1988·Australian and New Zealand Journal of Ophthalmology·A M BrooksW E Gillies
Sep 26, 2020·Indian Journal of Ophthalmology·Mona BhargavaShweta Patil
Apr 26, 2019·Journal of Biomedical Optics·Patrice TankamJannick P Rolland

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