Speech disorders in Parkinson's disease: pathophysiology, medical management and surgical approaches

Neurodegenerative Disease Management
Khashayar DashtipourBrianna Crawley

Abstract

The prevalence of speech disorders among individuals with Parkinson's disease (PD) has been reported to be as high as 89%. Speech impairment in PD results from a combination of motor and nonmotor deficits. The production of speech depends upon the coordination of various motor activities: respiration, phonation, articulation, resonance and prosody. A speech disorder is defined as impairment in any of its inter-related components. Despite the high prevalence of speech disorders in PD, only 3-4% receive speech treatment. Treatment modalities include pharmacological intervention, speech therapy, surgery, deep brain stimulation and vocal fold augmentation. Although management of Parkinsonian dysarthria is clinically challenging, speech treatment in PD should be part of a multidisciplinary approach to patient care in this disease.

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Citations

Feb 11, 2020·Neurodegenerative Disease Management·Davide FerrazzoliDaniele Volpe
Feb 14, 2020·Movement Disorders : Official Journal of the Movement Disorder Society·Zahra JafariMajid H Mohajerani
Sep 4, 2020·Journal of Neural Transmission·Olivier RascolUNKNOWN COPARK Study Group
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Nov 19, 2020·Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·N A Skripkina, A P Arefyeva
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Jul 29, 2021·Clinical Parkinsonism & Related Disorders·Matthew Dumican, Christopher Watts
Jul 13, 2021·Journal of Parkinson's Disease·Manon AuffretMarc Vérin
Aug 25, 2021·Brain Imaging and Behavior·Jinmei SunKai Wang
Jun 1, 2021·Digital Biomarkers·Guy FagherazziVladimir Despotovic

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Methods Mentioned

BETA
pharmacotherapy

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