PMID: 7031185Sep 1, 1981Paper

Speech disorders of Parkinsonism: a review

Journal of Neurology, Neurosurgery, and Psychiatry
E M Critchley

Abstract

Study of the speech disorders of Parkinsonism provides a paradigm of the integration of phonation, articulation and language in the production of speech. The initial defect in the untreated patient is a failure to control respiration for the purpose of speech and there follows a forward progression of articulatory symptoms involving larynx, pharynx, tongue and finally lips. There is evidence that the integration of speech production is organised asymmetrically at thalamic level. Experimental or therapeutic lesions in the region of the inferior medial portion of ventro-lateral thalamus may influence the initiation, respiratory control, rate and prosody of speech. Higher language functions may also be involved in thalamic integration: different forms of anomia are reported with pulvinar and ventrolateral thalamic lesions and transient aphasia may follow stereotaxis. The results of treatment with levodopa indicates that neurotransmitter substances enhance the clarity, volume and persistence of phonation and the latency and smoothness of articulation. The improvement of speech performance is not necessarily in phase with locomotor changes. The dose-related dyskinetic effects of levodopa, which appear to have a physiological basis i...Continue Reading

Associated Clinical Trials

References

Mar 6, 1976·Lancet·E M Critchley
Jun 26, 1976·Lancet
Sep 1, 1979·The American Journal of Cardiology·J P Finley, M B Waxman
Jan 1, 1977·Neuropsychologia·S E BlumsteinA Caramazza
Jan 1, 1975·Brain and Language·J M Van Buren
Jan 1, 1975·Brain and Language·M Riklan, I S Cooper
Jan 1, 1975·Brain and Language·F L DarleyW M Swenson
Apr 1, 1976·Postgraduate Medical Journal·D B Calne, J Fermaglich
Nov 21, 1970·Lancet·E M Critchley
Dec 5, 1970·Lancet·P FlemingK R Hunter
Feb 20, 1971·Lancet·A Barbeau
Feb 28, 1970·Lancet·P MillacD G Slyfield
Jun 27, 1970·Lancet·O W Sacks, M Kohl
Oct 1, 1973·Archives of Neurology·M C BatesonR S Wilson
Oct 1, 1973·Neurology·F BollerM Albert
Jan 1, 1968·Brain : a Journal of Neurology·D S Bell
Jan 2, 1971·British Medical Journal·R C HughesJ N Walton
Jan 1, 1971·Brain : a Journal of Neurology·G A Ojemann, A A Ward
Aug 1, 1971·Journal of Neurosurgery·G A OjemannA A Ward
Mar 1, 1968·Brain : a Journal of Neurology·G A OjemannJ M Van Buren
Dec 1, 1956·Journal of the American Geriatrics Society·Z LASZEWSKI
Jan 1, 1957·Acta psychiatrica et neurologica Scandinavica·F GREWEL
Sep 12, 1964·British Medical Journal·F J GILLINGHAMA A DONALDSON
Sep 1, 1950·The Journal of Speech Disorders·W G PEACHER

❮ Previous
Next ❯

Citations

Feb 24, 2001·Movement Disorders : Official Journal of the Movement Disorder Society·J Shahed, J Jankovic
Jun 8, 2001·Movement Disorders : Official Journal of the Movement Disorder Society·E D LouisB Ford
Sep 1, 1995·Movement Disorders : Official Journal of the Movement Disorder Society·C StewartM F Brin
Sep 1, 1992·Journal of Psycholinguistic Research·A J FlintC Levinton
Jun 18, 2002·Journal of Communication Disorders·Alexander GobermanMichael Robb
Jan 6, 2000·Journal of Voice : Official Journal of the Voice Foundation·J JiangD Hanson
Sep 18, 2009·Journal of the International Neuropsychological Society : JINS·Abhishek Jaywant, Marc D Pell
Jan 6, 2009·Telemedicine Journal and E-health : the Official Journal of the American Telemedicine Association·Lyn R TindallHarold L Kleinert
Aug 1, 1983·Journal of Neurology, Neurosurgery, and Psychiatry·A E Lang, V Fishbein
Jun 1, 1985·Journal of Neurology, Neurosurgery, and Psychiatry·D E Hartman, J H Abbs
Jun 1, 1985·Journal of Neurology, Neurosurgery, and Psychiatry·J Backon
Feb 1, 1991·Journal of Neurology, Neurosurgery, and Psychiatry·J F CaekebekeR A Roos
Aug 17, 2000·Journal of Neurology, Neurosurgery, and Psychiatry·T BenkeB Butterworth
Nov 24, 2004·Stereotactic and Functional Neurosurgery·Beau B BruceMichael S Okun
Jul 7, 2010·International Journal of Speech-language Pathology·Miet De LetterPatrick Santens
Feb 2, 2016·The Journal of the Acoustical Society of America·J R Orozco-ArroyaveE Nöth
Jun 1, 1991·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·D NatsopoulosJ Logothetis
Dec 1, 1996·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·M D Pell
Dec 14, 2004·Movement Disorders : Official Journal of the Movement Disorder Society·Anna Lena TörnqvistStig Rehncrona
Jun 23, 2012·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Jayam P LazarusMadhuri Behari
Nov 15, 2011·Journal of the Neurological Sciences·I RektorovaT Paus
Sep 8, 2009·Journal of the Neurological Sciences·Christine SchröderReinhard Dengler
Aug 5, 2008·Journal of the Neurological Sciences·S SachinM Behari
Aug 10, 1999·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·A J Lloyd
Aug 9, 2007·Movement Disorders : Official Journal of the Movement Disorder Society·Irena RektorovaTomas Paus
Mar 1, 2008·Movement Disorders : Official Journal of the Movement Disorder Society·Janine MöbesChristine Schröder
Jul 11, 2006·Movement Disorders : Official Journal of the Movement Disorder Society·Christine SchröderReinhard Dengler
Nov 19, 2013·IEEE Journal of Biomedical and Health Informatics·Sunghoon Ivan LeeMajid Sarrafzadeh
Jul 1, 1987·IEEE Transactions on Bio-medical Engineering·I Gath, E Yair
Mar 8, 2005·Journal of Communication Disorders·Miet De LetterJohn Van Borsel
May 1, 1992·Brain and Language·M GrossmanH I Hurtig
Feb 1, 1989·Brain and Language·L X BlonderR C Gur
Mar 22, 2015·Journal of Voice : Official Journal of the Voice Foundation·Yukiko IkuiFumiaki Tanaka
Aug 25, 2004·Lancet Neurology·Serge PintoPascal Auzou
Dec 1, 1995·Journal of Speech and Hearing Research·L O RamigY Horii
Nov 16, 2001·Journal of Speech, Language, and Hearing Research : JSLHR·J KleinowL O Ramig
Apr 1, 1993·Journal of Speech and Hearing Research·N P Solomon, T J Hixon

❮ Previous
Next ❯

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.