Speeding along the protein folding highway, are we reading the signs correctly?

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Speeding along the protein folding highway, are we reading the signs correctly?

Abstract

References

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NMR determination of residual structure in a urea-denatured protein, the 434-repressor

Hydrogen exchange in thermally denatured ribonuclease A

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NMR evidence for an early framework intermediate on the folding pathway of ribonuclease A

Conformation of peptide fragments of proteins in aqueous solution: implications for initiation of protein folding

Spin glasses and the statistical mechanics of protein folding

Watching protein folding unfold

Extremely rapid protein folding in the absence of intermediates

The energetic ups and downs of protein folding

The barriers in protein folding

The nature of protein folding pathways: the classical versus the new view

Toward an outline of the topography of a realistic protein-folding funnel

Characterizing transition states in protein folding: an essential step in the puzzle

Funnels, pathways, and the energy landscape of protein folding: a synthesis

Navigating the folding routes

Protein folding. Solid evidence for molten globules

Primary structure effects on peptide group hydrogen exchange

Formation of a molten globule intermediate early in the kinetic folding pathway of apomyoglobin

Peptide models of protein folding initiation sites. 1. Secondary structure formation by peptides corresponding to the G- and H-helices of myoglobin

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Peptide models of protein folding initiation sites. 3. The G-H helical hairpin of myoglobin

Evidence for a three-state model of protein folding from kinetic analysis of ubiquitin variants with altered core residues

Nonrandom distribution of the one-disulfide intermediates in the regeneration of ribonuclease A

Structure of a hydrophobically collapsed intermediate on the conformational folding pathway of ribonuclease A probed by hydrogen-deuterium exchange

Fast-folding experiments and the topography of protein folding energy landscapes

Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: conformational disorder mediates binding diversity

Observation of distinct nanosecond and microsecond protein folding events

Microsecond protein folding through a compact transition state

From Levinthal to pathways to funnels

Kinetic role of early intermediates in protein folding

Nucleation mechanisms in protein folding

On-pathway versus off-pathway folding intermediates

Optimum superimposition of protein structures: ambiguities and implications

Structure of very early protein folding intermediates: new insights through a variant of hydrogen exchange labelling

Protein folding funnels: the nature of the transition state ensemble

The C-terminal half of the anti-sigma factor, FlgM, becomes structured when bound to its target, sigma 28

The kinetic folding intermediate of ribonuclease H resembles the acid molten globule and partially unfolded molecules detected under native conditions

Characterization of long-range structure in the denatured state of staphylococcal nuclease. II. Distance restraints from paramagnetic relaxation and calculation of an ensemble of structures

Diffusion control in an elementary protein folding reaction

Molecular collapse: the rate-limiting step in two-state cytochrome c folding

Protein folding: does diffusion determine the folding rate?

Laser temperature jump study of the helix<==>coil kinetics of an alanine peptide interpreted with a 'kinetic zipper' model

Ultrafast signals in protein folding and the polypeptide contracted state

Structure of a kinetic protein folding intermediate by equilibrium amide exchange

Acquisition of native beta-strand topology during the rapid collapse phase of protein folding

Slow cooperative folding of a small globular protein HPr

Chemical shift dispersion and secondary structure prediction in unfolded and partly folded proteins

The C-terminal half of the anti-sigma factor FlgM contains a dynamic equilibrium solution structure favoring helical conformations

Citations

Visualizing transient protein-folding intermediates by tryptophan-scanning mutagenesis.

Multiple pathways on a protein-folding energy landscape: kinetic evidence

Time-dependent changes in side-chain solvent accessibility during cytochrome c folding probed by pulsed oxidative labeling and mass spectrometry

Protein stability and ligand binding: new paradigms from in-silico experiments

Kinetic and equilibrium intermediate states are different in LYLA1, a chimera of lysozyme and alpha-lactalbumin

Unfolded in vacuo lysozyme folds into native, quasinative, and compact structures

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