Dec 1, 1987

Sperm auto-immunity associated with vasectomy, vasovasostomy and epididymovasostomy in Korean males

Clinical Reproduction and Fertility
H Y LeeS I Kim

Abstract

The prevalence and pattern of circulating antisperm antibodies were assessed in the serum of Korean males undergoing vasectomy, vasovasostomy, epididymovasostomy and in a control group of men with normal semen by means of the gelatin agglutination test and the tray agglutination test. Sperm-agglutinating antibodies in serum were positive at a titre of 1:32 or greater in 3% of normospermic control males and in 27% of vasectomized men. No significant changes were observed in prevalence of the antibodies over the period following vasectomy. There were no significant differences in prevalence of antibodies in patients with and without postoperative sperm granulomas. Antibodies were positive in 35% of vasectomized men just prior to vasovasostomy and in 29% of patients 12 months after a successful (patent) reversal operation. There was no significant difference in prevalence of antibodies in patients with successful and unsuccessful vasovasostomies. Antibodies were positive in 20% of men who achieved pregnancies and in 43% of those with persisting infertility in the presence of a patent vasovasostomy. Sperm agglutinating antibodies were present in 5% of the patients with pathological epididymal obstruction. They were negative in pati...Continue Reading

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Mentioned in this Paper

Seminal Fluid
Autoantibodies
Epididymis
Semen
Phosphoglycerate Dehydrogenase Activity
Vasovasostomy
Vasal
Obstruction
Observation Method - Agglutination
PHGDH wt Allele

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