Sperm nuclei entering parthenogenetically activated mouse oocytes before the first mitosis transform into pronuclei. An ultrastructural study

The Anatomical Record
M Maleszewski

Abstract

This report is an extension of previous observations (Maleszewski 1992. Mol. Reprod. Dev., 33:215-221) on the behavior of mouse sperm nuclei incorporated into parthenogenetically activated mouse oocytes prior to the first cleavage division and undergoing transformation during mitosis. Artificially activated mouse oocytes were inseminated in vitro and an ultrastructural analysis was performed of sperm-derived nuclei present in two parthenogenetic two-cell embryos. Both chromatin and nuclear envelope of sperm derived-nuclei are structurally identical with those of oocyte-derived nuclei and of the nuclei of blastomeres of normal two-cell embryos. Cytoplasm of the parthenogenote during the first mitotic division has the ability to transform sperm nucleus into a male pronucleus just like the cytoplasm of a metaphase II oocyte.

References

Jun 1, 1975·Developmental Biology·D W Fawcett
Jan 1, 1991·Molecular Reproduction and Development·P G AdenotP Debey
Jul 1, 1980·Experimental Cell Research·H Bałakier, A K Tarkowski
Feb 1, 1994·Molecular Reproduction and Development·M S SzöllösiD Szöllösi

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Citations

Feb 1, 1997·Zygote : the Biology of Gametes and Early Embryos·N UsuiR Yanagimachi
Feb 3, 2005·Molecular Reproduction and Development·Berenika PłusaJacek A Modliński

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