Sperm quality and ambient air pollution exposure: A retrospective, cohort study in a Southern province of China

Environmental Research
Guanhao HuangQingguo Zhao

Abstract

Abnormal semen quality is one of the common causes of infertility. The relationship between exposure to air pollutants and semen quality is unclear. To evaluate the impact of ambient air pollutant exposures on semen quality. We analyzed 3797 semen samples from Guangdong Human Sperm Bank between May 28, 2018 and March 31, 2019. The inverse distance weighted interpolation method was used to estimate the personal exposures to CO, SO2, NO2, O3, PM10 and PM2.5 during the entire period (0-90 lag days) and key periods (0-9, 10-14, 70-90 lag days) of sperm development. Linear mixed models were used to evaluate the exposure-response relationships between air pollutants and semen quality, including sperm concentration, sperm count and sperm motility, after adjusting for other covariates. The regression coefficients and 95% confidence intervals (CIs) associated with each interquartile range (IQR) increase in pollutant concentrations were estimated for each semen quality parameter. Overall, we observed a significant association of decreased sperm count with the exposure to PM10 (-0.2466; -0.4443, -0.0489) and PM2.5 (-0.2910; -0.5401, -0.0419). Among the sperm quality parameters assessed, sperm count was observed more frequently to be negat...Continue Reading

Citations

Feb 6, 2021·Reviews on Environmental Health·Sunil KumarRiddhi Thaker
Aug 13, 2021·PloS One·Seung-Ah ChoeDae Keun Kim
Sep 18, 2021·Environmental Science and Pollution Research International·Hong QianChuncheng Lu
Oct 12, 2021·PeerJ·Yinghong ChenGuoping Li

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