PMID: 6159556Nov 27, 1980Paper

Sperm-specific surface antigenicity common to seven animal phyla

Nature
A C Lopo, V D Vacquier

Abstract

While studying the plasma membrane of sperm of the sea urchin Strongylocentrotus purpuratus, we developed an antiserum that exhibits unusual reactivity--it cross-reacts with the surfaces of spermatozoa of 28 species representing seven phyla of the animal kingdom. A negative cross-reaction has not been found. This suggests the possible existence of common antigenic determinants on the surface of all animal sperm. We report these preliminary results here because of the broad implications common sperm-surface antigenicity has for the potential development of immunocontraceptive methods.

References

Aug 1, 1976·Developmental Biology·D Solter, M Schachner
Mar 11, 1977·Science·W K Silvers, S S Wachtel
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Feb 1, 1978·The Journal of Experimental Zoology·G J Allen, F J Bourne
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May 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·G C KooM P Lardis
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Citations

Jul 18, 2000·Theriogenology·S KalaydjievL Nakov
Jun 4, 2002·Theriogenology·S K Kalaydjiev
Sep 13, 2008·Reproduction : the Official Journal of the Society for the Study of Fertility·Ashley I YudinCharles L Bevins
Jan 1, 1982·Annals of the New York Academy of Sciences·A C LopoV D Vacquier
Mar 1, 1981·Immunology Today·T G Wegmann

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