Sphenopalatine artery ligation with nerve resection in patients with vasomotor rhinitis and polyposis: a prospective, randomized, double-blind investigation

Acta Oto-laryngologica
Michele CassanoPasquale Cassano

Abstract

Sphenopalatine artery ligation relieves symptoms of rhinorrhea, sneezing, and nasal itching in patients with vasomotor rhinitis associated with nasal polyps. Nasal polyps often arise in a setting of vasomotor rhinitis. Dysfunctions in nerve fiber activity of the sympathetic and parasympathetic systems are responsible for the accompanying symptoms of rhinorrhea, sneezing, and nasal itching. Sphenopalatine pedicle resection with autonomic denervation could potentially reduce related symptoms. In a prospective, double-blind setting, 60 patients with vasomotor rhinitis and bilateral nasal polyps randomly assigned to functional endoscopic surgery either with (group A) or without (group B) sphenopalatine artery ligation completed a 3-year follow-up. Preoperative and postoperative (at 1 and 3 years) evaluations included symptom score, fiberendoscopy, and active anterior rhinomanometry. In both treatment groups nasal breathing had improved at 1-year and 3-year follow-up (p < 0.001), whereas an improvement in rhinorrhea (p < 0.001) and sneezing and itching (p < 0.01) was attained only in group A. The inter-group comparison showed that a statistically significant improvement in rhinorrhea and nasal itching (p = 0.002) and in sneezing (p ...Continue Reading

References

Dec 1, 1992·The Laryngoscope·R Budrovich, R Saetti
Feb 1, 1986·The Laryngoscope·F Bagatella
Apr 1, 1995·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·C M ShaariH F Biller
Jun 1, 1997·Journal of Pain and Symptom Management·A Prasanna, P S Murthy
Jan 12, 1999·American Journal of Rhinology·S Marks
Apr 29, 1999·American Journal of Rhinology·C H SnydermanJ R Grandis
Jun 29, 2006·Acta Oto-laryngologica·Katsuhisa IkedaAkira Shimomura
Nov 15, 2007·American Journal of Rhinology·Seth J Isaacs, Parul Goyal
Feb 20, 2009·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Samy ElwanyOsama Abu el-Kheir
Aug 29, 2009·Auris, Nasus, Larynx·Michele CassanoAlessandro Maselli Del Giudice

❮ Previous
Next ❯

Citations

Aug 5, 2016·The Journal of Laryngology and Otology·T MarshakR J Harvey
Jul 23, 2019·International Forum of Allergy & Rhinology·Eric W WangCarl H Snyderman
Dec 24, 2017·Surgical and Radiologic Anatomy : SRA·Daniel Fossum BratbakErling Tronvik

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adenomatous Polyposis Coli

Adenomatous polyposis coli is a protein encoded by the APC gene and acts as a tumor suppressor. Discover the latest research on adenomatous polyposis coli here.