Spider silk as archetypal protein elastomer

Soft Matter
Fritz Vollrath, D Porter

Abstract

We present an overview of the physical properties of spider silks, and introduce a model designed to study the energy absorbed by the material as it stretches before breaking. Of particular interest are the inter- and intramolecular hydrogen bonds as well as the role of water in modifying the material properties of silk. A solid understanding of this interaction is of paramount importance for any deeper insights into the mechanical properties of any biomaterial. Here we note that the typical biological material has evolved to function in the fully hydrated elastomeric state. We conclude that silk after its transformation from the hydrated feedstock to the dehydrated fibre state can in fact be analysed in great detail and interpreted as representative of a wide range of elastomeric proteins covering, inter alia, bone, keratins, elastin and collagen.

References

Aug 1, 1989·International Journal of Biological Macromolecules·J J Thwaites, N H Mendelson
Mar 1, 1983·Ultrastructural Pathology·D W Urry
Jun 1, 1996·Protein Expression and Purification·R V LewisM J Fournier
Apr 16, 1998·Protein Science : a Publication of the Protein Society·M A Colgin, R V Lewis
Sep 2, 1998·Journal of Structural Biology·P FratzlS Bernstorff
May 26, 1999·International Journal of Biological Macromolecules·C RiekelM Müller
May 26, 1999·International Journal of Biological Macromolecules·D T Grubb, G Ji
May 26, 1999·International Journal of Biological Macromolecules·F Vollrath, D P Knight
May 26, 1999·International Journal of Biological Macromolecules·S WinklerD Kaplan
May 26, 1999·International Journal of Biological Macromolecules·C Y HayashiR V Lewis
May 26, 1999·International Journal of Biological Macromolecules·B MadsenF Vollrath
Mar 30, 2001·Nature·F Vollrath, D P Knight
Oct 9, 2001·International Journal of Biological Macromolecules·C Riekel, F Vollrath
Nov 13, 2001·Proceedings. Biological Sciences·F VollrathZ Shao
Jan 5, 2002·Journal of Biotechnology·S Winkler, D L Kaplan
Jan 19, 2002·Science·Anthoula LazarisCostas N Karatzas
Mar 8, 2002·Nature·Fraser I BellChristopher Viney
May 30, 2002·Biophysical Chemistry·Felix Franks
Aug 1, 2002·Proceedings of the National Academy of Sciences of the United States of America·J D van BeekB H Meier
Aug 16, 2002·Nature·Zhengzhong Shao, Fritz Vollrath
Nov 9, 2002·Biomaterials·Gregory H AltmanDavid L Kaplan
Jan 1, 1997·Annual Review of Entomology·C L Craig
May 11, 2004·Biomacromolecules·Regina Valluzzi, Hyoung-Joon Jin
Feb 25, 2005·The European Physical Journal. E, Soft Matter·D PorterZ Shao
Mar 23, 2005·Biochemistry·Alexander SponnerKlaus Weisshart
May 12, 2005·Chemical Communications : Chem Comm·Yi LiuFritz Vollrath
Aug 3, 2005·Proceedings of the National Academy of Sciences of the United States of America·Jessica E Garb, Cheryl Y Hayashi
Oct 27, 1989·Science·W A ShearP M Bonamo

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Citations

Sep 8, 2011·Angewandte Chemie·Aaron M Kushner, Zhibin Guan
Jan 9, 2013·Advanced Materials·Steven W CranfordMarkus J Buehler
Dec 6, 2016·International Journal of Molecular Sciences·Geoffrey M GrayGregory P Holland
Aug 5, 2017·Materials·Dave JaoXiao Hu
Aug 15, 2017·Nature Materials·Mehra S SidhuKamal P Singh
Aug 3, 2010·HFSP Journal·Markus J Buehler, Yu Ching Yung
Oct 14, 2011·Biopolymers·Alejandro D Rey, Edtson E Herrera-Valencia
Oct 30, 2009·Chemical Communications : Chem Comm·Chengjie FuVollrath Fritz
Jan 18, 2011·Physical Chemistry Chemical Physics : PCCP·Maxime Boulet-AudetChris Holland
Jun 7, 2014·Nanoscale·Yuan Chen, Yongmei Zheng
Jun 9, 2018·Advanced Materials·Thomas O Mason, Ulyana Shimanovich
Dec 27, 2017·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Michael C Jarvis
May 19, 2018·Advanced Materials·Yuchao WuOren A Scherman
Dec 11, 2019·Materials·Amrita SarkarR Helen Zha
Jul 2, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Gabriele Greco, Nicola M Pugno
Oct 24, 2006·Nature Materials·C HollandF Vollrath
Sep 14, 2007·European Biophysics Journal : EBJ·Arne SchäferTim Salditt
Dec 20, 2013·Advanced Materials·Hannes C SchnieppFritz Vollrath
Jan 17, 2014·Advanced Materials·Tristan GiesaMarkus J Buehler
Feb 26, 2013·Analytical and Bioanalytical Chemistry·Xiangyan ShiGregory P Holland
Feb 9, 2012·Biological Reviews of the Cambridge Philosophical Society·André Walter, Mark A Elgar
Sep 16, 2016·Journal of the Royal Society, Interface·Igor KrasnovMartin Müller
Sep 13, 2016·International Journal of Molecular Sciences·Tetsuo AsakuraYugo Tasei
Apr 2, 2019·Nature Communications·Taiyo YoshiokaTsunenori Kameda
Dec 18, 2019·Nature Materials·Chengchen GuoDavid L Kaplan
Jun 28, 2016·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Guangqiang FangXin Chen
Jan 22, 2008·Soft Matter·D Porter, F Vollrath
Oct 16, 2015·Advanced Healthcare Materials·Yihua LooAnna Mitraki
Jan 15, 2015·Angewandte Chemie·Soumyajit GhoshGautam R Desiraju
Jul 20, 2017·Macromolecular Bioscience·Kousuke Tsuchiya, Keiji Numata
Feb 20, 2018·Macromolecular Rapid Communications·Tanner D Fink, R Helen Zha
Apr 10, 2019·Scientific Reports·Gabriele GrecoNicola M Pugno
Jan 11, 2019·Biomaterials Science·R Helen ZhaPhillip B Messersmith
Dec 4, 2019·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Qinglin DongXin Chen
Feb 23, 2012·PloS One·Andrew A WalkerTara D Sutherland

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