PMID: 7543940Jan 1, 1995Paper

Spinal cord compression in prostate cancer

Journal of Neuro-oncology
J L OsbornD L Trump

Abstract

Approximately 200,000 men will be diagnosed with prostate cancer in 1994. While localized disease is potentially curable with surgery or radiation therapy, metastatic disease is incurable. The most frequent site of metastasis is bone. Spinal cord compression occurs in approximately 7% of men with prostate cancer. Back pain often heralds the diagnosis of spinal cord compression. In prostate cancer patients with back pain or signs of myelopathy or radiculopathy, plain radiographs of the spine and magnetic resonance imaging should be performed. Early diagnosis is of utmost importance. The neurologic status prior to treatment is the major determinant influencing outcome. Following diagnosis, corticosteroid therapy should begin immediately. Hormonal therapy should be instituted in those patients who have not previously undergone hormonal manipulation. The standard approach to definitive therapy is radiation. Surgical decompression plays a role in patients with severe myelopathy, spinal instability, and in those patients whose neurologic status deteriorates during or after radiation therapy.

References

May 1, 1977·Neurology·Y UshioW R Shapiro
Jan 1, 1978·Annals of Neurology·R W GilbertJ B Posner
Sep 1, 1977·Journal of Neurosurgery·Y UshioJ B Posner
Aug 27, 1992·The New England Journal of Medicine·T N Byrne
May 1, 1992·British Journal of Urology·M A RosenthalB Pearson
May 1, 1991·Neurology·H J KaminskiR L Ruff
Feb 22, 1990·The New England Journal of Medicine·J A Bonner, A S Lichter
Jan 1, 1989·Annual Review of Immunology·P W KincadeJ M Gimble
Jul 1, 1989·The Journal of Clinical Investigation·M Chackal-RoyB R Zetter
Aug 1, 1987·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·J C KirchheimerB R Binder
Mar 1, 1988·In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association·W L McKeehan, P S Adams
Dec 1, 1985·British Journal of Urology·J W IacovouA J Ball
Apr 1, 1983·Urology·S C Jacobs
Jun 1, 1981·The American Journal of Medicine·L D RodichokJ Horton
Jan 1, 1983·Journal of Neuro-oncology·S G TangS L Seagren
Jul 1, 1983·Journal of Neurosurgery·J P ConstansC Haye
Mar 1, 1982·Brain : a Journal of Neurology·R J StarkS J Evans
May 1, 1994·Journal of Cellular Biochemistry·R H Getzenberg
May 1, 1994·International Journal of Cancer. Journal International Du Cancer·H C WuL W Chung
Feb 1, 1993·The Journal of Urology·E M SmithM I Resnick
Jun 24, 2010·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Li YangGregory R Mundy

❮ Previous
Next ❯

Citations

Jan 1, 1997·Neurosurgical Review·K NanassisR A Frowein
Apr 19, 2006·Current Oncology Reports·Fred Saad
Dec 12, 2003·European Urology·Fred Saad, Claude C Schulman
Oct 24, 2003·European Urology·H TaziF Guillé
Sep 14, 2013·Human Gene Therapy·Olga ZolochevskaMarxa L Figueiredo
Feb 9, 2006·Neurosurgical Focus·J M Schuster, M S Grady
Apr 9, 2004·Journal of Neurosurgery·Stephen J HentschelLaurence D Rhines
Jan 1, 2007·Indian Journal of Urology : IJU : Journal of the Urological Society of India·Pratipal Singh, Aneesh Srivastava
Feb 16, 2000·The British Journal of Radiology·M A Long, J E Husband
Mar 1, 2011·Urologic Oncology·Luca Dalle CarbonareMaria Teresa Valenti
Mar 30, 2004·Clinical Prostate Cancer·Luis E CerecedaJean-Pierre Droz
Nov 27, 2007·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Ramachandran VenkitaramanS Aslam Sohaib
May 15, 2007·Clinical Oncology : a Journal of the Royal College of Radiologists·R VenkitaramanD P Dearnaley
Nov 18, 2003·BJU International·N W Clarke
Jun 27, 2006·European Urology·Noel W Clarke
Jun 11, 1999·The Urologic Clinics of North America·P Esper, B G Redman
Sep 25, 2012·Clinical Neurology and Neurosurgery·Laura ColumbanoWolf Luedemann
May 11, 2016·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Amparo WolfFawaz Siddiqi
Jan 15, 2004·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Kiyomitsu OyanagiTakashi Morita
Dec 3, 2005·Acta neurochirurgica·R DeinsbergerH C Bankl
Sep 10, 2005·Journal of Neuro-oncology·R DeinsbergerH C Bankl
Jun 17, 2005·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Sten NilssonOyvind S Bruland

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.