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SPION decorated exosome delivery of TNF-α to cancer cell membranes through magnetism

Nanoscale

Dec 6, 2019

Manjiao ZhuangLei Rao

Abstract

Tumor necrosis factor (TNF-α) is capable of inducing apoptosis and is a promising candidate for genetic engineering drugs in cancer therapy; however, the serious side-effects of TNF-α hinder their clinical application. In the present study, a method for preparing fusion proteins of cell...read more

Mentioned in this Paper

Tumor Necrosis Factor-alpha
Membrane receptor
Biochemical Pathway
Melanoma
Mus
Antineoplastic Agents
Exosomes
Transferrin Receptor
Tumor Cells, Malignant
Study
3
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SPION decorated exosome delivery of TNF-α to cancer cell membranes through magnetism

Nanoscale

Dec 6, 2019

Manjiao ZhuangLei Rao

PMID: 31803890

DOI: 10.1039/c9nr05865f

Abstract

Tumor necrosis factor (TNF-α) is capable of inducing apoptosis and is a promising candidate for genetic engineering drugs in cancer therapy; however, the serious side-effects of TNF-α hinder their clinical application. In the present study, a method for preparing fusion proteins of cell...read more

Mentioned in this Paper

Tumor Necrosis Factor-alpha
Membrane receptor
Biochemical Pathway
Melanoma
Mus
Antineoplastic Agents
Exosomes
Transferrin Receptor
Tumor Cells, Malignant
Study
3

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