Spiracular air breathing in polypterid fishes and its implications for aerial respiration in stem tetrapods

Nature Communications
Jeffrey B GrahamJohn A Long

Abstract

The polypterids (bichirs and ropefish) are extant basal actinopterygian (ray-finned) fishes that breathe air and share similarities with extant lobe-finned sarcopterygians (lungfishes and tetrapods) in lung structure. They are also similar to some fossil sarcopterygians, including stem tetrapods, in having large paired openings (spiracles) on top of their head. The role of spiracles in polypterid respiration has been unclear, with early reports suggesting that polypterids could inhale air through the spiracles, while later reports have largely dismissed such observations. Here we resolve the 100-year-old mystery by presenting structural, behavioural, video, kinematic and pressure data that show spiracle-mediated aspiration accounts for up to 93% of all air breaths in four species of Polypterus. Similarity in the size and position of polypterid spiracles with those of some stem tetrapods suggests that spiracular air breathing may have been an important respiratory strategy during the fish-tetrapod transition from water to land.

References

May 1, 1988·Journal of Comparative Physiology. A, Sensory, Neural, and Behavioral Physiology·M A BarryM V Bennett
May 1, 1988·Journal of Comparative Physiology. A, Sensory, Neural, and Behavioral Physiology·M A BarryM V Bennett
Jan 20, 2006·Nature·Martin D Brazeau, P E Ahlberg
Apr 7, 2006·Nature·Edward B DaeschlerFarish A Jenkins
Oct 20, 2006·Nature·John A LongErich M G Fitzgerald
Dec 22, 1989·Science·E L BrainerdC T Samper
Jun 27, 2008·Nature·P E AhlbergIvars Zupiņs
Oct 1, 2007·Integrative and Comparative Biology·Jennifer A Clack
Aug 1, 1989·Journal of Morphology·A LechleuthnerU Welsch

Citations

May 23, 2015·Journal of Anatomy·Benjamin C WilhelmHans C E Larsson
Apr 29, 2015·PloS One·J S AndersonJennifer A Clack
Mar 9, 2017·Proceedings of the National Academy of Sciences of the United States of America·Malcolm A MacIverCurtis D Mobley
Nov 1, 2018·Wiley Interdisciplinary Reviews. Developmental Biology·April DeLaurier
Feb 2, 2019·Journal of Morphology·Andy J TurkoEmily M Standen
Jun 17, 2016·Proceedings. Biological Sciences·J S AndersonA Tinius
Oct 25, 2019·Nature·Nadia B Fröbisch, Florian Witzmann
Feb 3, 2021·Proceedings of the National Academy of Sciences of the United States of America·Justin B LembergNeil H Shubin

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