Spitz nevus in a Hispanic population: a clinicopathological study of 130 cases

The American Journal of Dermatopathology
Alma C Berlingeri-RamosElena M Nogales

Abstract

Spitz nevus is an uncommon melanocytic nevus distinctive by its epithelioid and spindled melanocytes. Many studies have attempted to characterize Spitz nevus, but none of them in a Hispanic population. Our aim is to characterize the clinical and histopathological presentation of the Spitz nevus in a Hispanic population. A retrospective study was carried out from our files that included those cases histopathologically diagnosed as Spitz nevus. A blinded examination was performed to evaluate the histopathological characteristics of 130 lesions. The demographics of the patients, the anatomic location, and the accuracy of the clinical diagnosis were analyzed. Eighty-one females and 49 males (ratio of 1.7:1) were included in the study. The mean age was 18.8 years. Overall, the most common location was the lower extremities (41%), followed by the upper extremities (27%), trunk (16%), and head and neck (16%). The nevi followed a similar anatomic distribution in females and males. The lesions were clinically diagnosed with accuracy in 20% of the cases and characterized as a pigmented papule in 42% of the cases. Upon histopathological evaluation, most nevi exhibited symmetry (84%), were well circumscribed (91%), and exhibited epidermal ...Continue Reading

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Citations

Jun 23, 2012·Annales de dermatologie et de vénéréologie·L Le Saché-de PeufeilhouxS Fraitag
Feb 4, 2012·Journal of the American Academy of Dermatology·Maya ZayourRossitza Lazova
Dec 20, 2011·American Journal of Surgery·Sarah J Hill, Keith A Delman
May 14, 2016·Journal of the European Academy of Dermatology and Venereology : JEADV·C StefanakiA Stratigos
Feb 13, 2015·Anais Brasileiros De Dermatologia·Gustavo Costa Verardino, Mayra Carrijo Rochael
Nov 19, 2017·Journal of the European Academy of Dermatology and Venereology : JEADV·E SouraA Stratigos
Jul 15, 2017·Giornale Italiano Di Dermatologia E Venereologia : Organo Ufficiale, Società Italiana Di Dermatologia E Sifilografia·Paolo BroganelliMaria T Fierro
Jan 23, 2019·Journal of Cutaneous Pathology·Sophia A MaEmily Y Chu

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