Spleen and splenic vascular involvement in acute pancreatitis: an MRI study

Quantitative Imaging in Medicine and Surgery
Chao-Lian XieXiao-Ming Zhang

Abstract

To investigate the spleen and splenic vascular involvement in acute pancreatitis (AP) and their correlations with the severity of AP using magnetic resonance imaging (MRI). MRI of 239 patients with AP was retrospectively reviewed to assess splenic and splenic vascular complications, and the severity of AP. The severity of AP was graded by the MRI severity index (MRSI) and the New Revised Classification of AP 2012. The intravoxel incoherent motion (IVIM) parameters (D, D*, and f) of spleen were measured. Thirty-five subjects without pancreatic and splenic disorders were enrolled as controls for IVIM parameters. Among the 239 patients with AP, splenomegaly (16.7%), splenic infarction (0.4%), splenic vein thrombosis (4.2%), phlebitis (7.5%) and arteritis (4.2%) were observed. Splenic vascular involvement was positively correlated with the severity of AP based on both the MRSI and the New Revised Classification of AP 2012 (P<0.05). In the control and AP groups, the splenic f values were (0.164±0.074) vs. (0.210±0.095) (P=0.023) respectively. In AP patients with and without splenomegaly, f = (0.240±0.091) vs. (0.203±0.095) (P<0.001). Splenic vascular involvement and splenomegaly were common in AP. The vascular involvement was associ...Continue Reading

Citations

Apr 3, 2020·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Chengliang YangYufei Lu
Jul 6, 2021·Journal of Pediatric Gastroenterology and Nutrition·Chinenye R DikeAliye Uc

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