Splenectomy as part of cytoreductive surgery in ovarian cancer

Gynecologic Oncology
Paul M MagtibayKarl C Podratz

Abstract

Epithelial ovarian carcinoma with extensive upper abdominal disease may require splenectomy for optimal tumor cytoreduction. We describe patients who required splenectomy during tumor reduction procedures for primary or recurrent epithelial ovarian carcinoma. Data were abstracted from records of 112 patients who underwent splenectomy as part of primary or secondary cytoreductive surgery. Of 112 patients, 66 had primary and 46 had secondary cytoreduction. Some patients also required bowel resection (50%), formal lymphadenectomy (31%), or urinary tract resection (5%). The most common indications for splenectomy were direct metastatic involvement (46%), facilitation of an en bloc resection of perisplenic disease (41%), and intraoperative trauma (13%). Histologically, 65% had hilar involvement; 52%, capsular involvement; and 16%, parenchymal metastases. Short-term complications included wound infections (7), pneumonias (5), thromboembolic events (9), and sepsis (5). Sepsis was associated with an anastomotic bowel leak in 1 patient, with fungal infections in 2 patients (1 pneumonia and 1 pelvic abscess), and with no identifiable infectious source in 2. Two patients required reoperation for bleeding: 1 for diffuse intraabdominal blee...Continue Reading

References

Jan 19, 2002·The Journal of Infection·N BisharatR Raz
Mar 1, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Robert E BristowF J Montz
Sep 13, 2005·Gynecologic Oncology·Giovanni D AlettiWilliam A Cliby
Jan 6, 2006·Obstetrics and Gynecology·Giovanni D AlettiWilliam A Cliby

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Citations

Mar 8, 2014·Women's Health·Martin PölcherDennis S Chi
Mar 23, 2011·Annals of Surgical Oncology·Christopher K McCannAnnekathryn Goodman
Dec 1, 2012·Current Treatment Options in Oncology·Carrie Langstraat, William A Cliby
Jan 24, 2013·Archives of Gynecology and Obstetrics·Andrea Papadia, Matteo Morotti
Mar 29, 2011·European Journal of Radiology·Senem SenturkDeniz Akata
Nov 27, 2010·Journal of the American College of Surgeons·Ioannis T KonstantinidisCristina R Ferrone
Dec 17, 2009·Gynecologic Oncology·Francesco FanfaniGiovanni Scambia
Jun 7, 2007·Mayo Clinic Proceedings·Giovanni D AlettiLynn C Hartmann
Nov 26, 2008·Gynecologic Oncology·Giovanni D AlettiKirsten Hall Long
Nov 18, 2008·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·L VerleyeUNKNOWN Gynaecological Cancer Group (GCG) of European Organisation for Research and Treatment of Cancer (EORTC)
Dec 15, 2015·Journal of Cancer Research and Clinical Oncology·Maria Luisa GasparriAndrea Papadia
Sep 10, 2010·European Journal of Cancer Care·J Hanprasertpong, K Fujiwara
Jul 4, 2007·Surgical Oncology Clinics of North America·Elizabeth Suh-Burgmann, C Bethan Powell
Aug 11, 2007·American Journal of Obstetrics and Gynecology·Mitchel S HoffmanJorge Lockhart
Feb 25, 2015·Current Oncology Reports·Deepa Maheswari NarasimhuluDennis S Chi
Jul 10, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Amanda Nickles Fader, Peter G Rose
Jun 8, 2012·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Ignacio ZapardielAngelo Maggioni
Nov 22, 2013·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Kazuyoshi KatoMakio Shozu
Jan 16, 2007·Current Opinion in Obstetrics & Gynecology·Osamu Takahashi, Toshinobu Tanaka
Aug 5, 2010·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Catherine UzanPhillippe Morice
Mar 29, 2014·Experimental and Therapeutic Medicine·Meiling LvJin Yang
Feb 22, 2012·Clinical Obstetrics and Gynecology·Ritu Salani, Robert E Bristow
Jul 16, 2020·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Olga T FilippovaDennis S Chi
Jun 29, 2011·Revista do Colégio Brasileiro de Cirurgiões·Renato de Lima RozenowiczTsutomu Aoki
Nov 27, 2020·World Journal of Surgical Oncology·Antoni LluecaUNKNOWN on behalf MUAPOS Working Group
Dec 30, 2020·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·James DaviesAndrew Phillips
Aug 12, 2020·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Ulrika JoneborgSahar Salehi
Feb 17, 2019·American Journal of Obstetrics and Gynecology·Stephanie ChamJason D Wright

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