Splenic artery embolization with detachable balloons for hypersplenism

The Journal of International Medical Research
Xiaoxi PangCheng'en Wang

Abstract

Objective This study was performed to investigate the efficacy of proximal splenic artery embolization using detachable balloons for patients with hypersplenism and portal hypertension. Methods Twelve patients diagnosed with hypersplenism with thrombocytopenia or leukocytopenia caused by portal hypertension were treated by proximal splenic artery embolization with detachable balloons and metallic fibered coils. All patients were followed for up to 6 months. Blood parameters, coagulation factors, and liver function indicators were measured. Enhanced computed tomography and abdominal ultrasonography examinations were also performed in advance to confirm the infarction area and evaluate the changes in spleen size. Results Postoperative angiography demonstrated complete embolization of the proximal splenic artery in all 12 patients. Thrombocyte and leukocyte counts rose significantly in all patients in 2 weeks and stayed significantly higher than those before embolization throughout the 6-month follow-up. The total bilirubin concentration and prothrombin activity recovered significantly and returned to normal levels 6 months later. Computed tomography revealed partial infarction and liquefaction of the splenic parenchyma in nine pa...Continue Reading

References

Mar 22, 2002·Clinical and Experimental Pharmacology & Physiology·Yoshihiko OjiriMatao Sakanashi
Oct 18, 2005·Radiographics : a Review Publication of the Radiological Society of North America, Inc·David C MadoffMarshall E Hicks
Nov 24, 2007·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Hiroshi YoshidaTakashi Tajiri
Apr 17, 2008·The British Journal of Surgery·H HayashiH Baba
Jul 25, 2008·Nature·Ruslan Medzhitov
Dec 17, 2008·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·K ZhuH Shan
Nov 26, 2009·Journal of Gastroenterology and Hepatology·Morimasa TomikawaYoshihiko Maehara
May 6, 2010·Indian Journal of Gastroenterology : Official Journal of the Indian Society of Gastroenterology·Heba M AbdellaAli Z Helmy
Sep 21, 2010·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·A P N A de PortoJ B L Hoekstra
Jul 8, 2011·World Journal of Gastroenterology : WJG·Xin-Hong HeLi-Chao Xu
Jul 29, 2011·Journal of Gastroenterology and Hepatology·Tomohiko AkahoshiYoshihiko Maehara
Sep 27, 2012·Digestive Diseases and Sciences·John A HermosElizabeth V Lawler
Feb 26, 2013·AJR. American Journal of Roentgenology·Weiping WangCristiano Quintini
Feb 28, 2014·World Journal of Gastroenterology : WJG·Er-Sheng LiJun-Xiao Liu
May 31, 2014·World Journal of Radiology·Tyson A Hadduck, Justin P McWilliams

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Feb 29, 2020·Risk Management and Healthcare Policy·Lei ZhangWan-Guang Zhang

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