Splenic lymphoma with villous lymphocytes showing del(7) and inv(10)

Cancer Genetics and Cytogenetics
K F WongP K Hui

Abstract

A 49-year-old woman presented with splenic lymphoma with villous lymphocytes (SLVL) that showed a clonal abnormality of del(7)(q22q32) in addition to inv(10)(p13q23), the latter being a previously undescribed abnormality in chronic lymphoproliferative disorders. A review of the literature on cytogenetic abnormalities of SLVL indicates that del(7q) is strongly associated with SLVL and may be important in the pathogenesis of this disorder.

Citations

Aug 26, 2000·Cancer Genetics and Cytogenetics·Y KatayamaK Kohriyama
Feb 13, 2003·Cancer Genetics and Cytogenetics·Daniel HeintelUlrich Jaeger
May 18, 1999·Cancer Genetics and Cytogenetics·K F Wong, J K Chan
Dec 4, 2002·Genes, Chromosomes & Cancer·Alicja M Gruszka-WestwoodDaniel Catovsky
Nov 26, 2002·Blood·Vito FrancoEmilio Iannitto

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