journal cover

Spliceosomal RNA U6 is remarkably conserved from yeast to mammals

Nature

Jul 21, 1988

David A Brow, C Guthrie

Abstract

The small nuclear RNA U6 and its gene have been isolated from yeast. In striking contrast to other yeast spliceosomal RNAs, U6 is very similar in size, sequence and structure to its mammalian homologue. The single-copy gene is essential. These properties suggest a central role in pre-mR...read more

Mentioned in this Paper

RNA, Fungal
Small Nuclear RNA
Saccharomyces cerevisiae
RNA, Messenger, Splicing
Genes, Fungal
63
1
Paper Details
References
  • References33
  • Citations193

Spliceosomal RNA U6 is remarkably conserved from yeast to mammals

Nature

Jul 21, 1988

David A Brow, C Guthrie

PMID: 3041282

DOI: 10.1038/334213a0

Abstract

The small nuclear RNA U6 and its gene have been isolated from yeast. In striking contrast to other yeast spliceosomal RNAs, U6 is very similar in size, sequence and structure to its mammalian homologue. The single-copy gene is essential. These properties suggest a central role in pre-mR...read more

Mentioned in this Paper

RNA, Fungal
Small Nuclear RNA
Saccharomyces cerevisiae
RNA, Messenger, Splicing
Genes, Fungal
63
1
Paper Details
References
  • References33
  • Citations193
/papers/spliceosomal-rna-u6-is-remarkably-conserved-from/3041282