Abstract
To investigate the visualization of mediastinal lymph nodes during thoracic CT employing a multiphasic contrast media (CM) protocol. Institutional review board approved retrospective study consisting of 300 patients with known chest malignancy. Patients were allocated to one of two CM protocols: Protocol A, consisted of dual bolus (Phase 1:100 ml CM followed by 100 ml saline chaser) i.v. injected at 2.5 ml s-1; Protocol B employed 100 ml of CM using a multiphasic injection protocol (Phase 1 and 2:60 ml contrast and saline, followed by Phase 3 and 4:40 ml contrast and saline injected at 2.5 ml s-1) with a fixed scan delay of 70 s for each acquisition. Attenuation profiles of the thoracic arteries and veins were calculated as well as the arterio-venous contrast ratios (AVCR). Receiver operating characteristic (ROC), visual grading characteristic (VGC), and Cohen's kappa analysis were assessed. Arterial opacification was up to 24% (p < 0.032) higher in protocol B than A, whereas, in the veins it was significantly lower in protocol B than A, with a maximum reduction of up to 84% (p < 0.0001). There was no statistical significance between the central and peripheral pulmonary arteries [>263 Hounsfield units (HU)] in each protocol. Pr...Continue Reading
References
Apr 28, 2006·The British Journal of Radiology·T Suwatanapongched, D S Gierada
Apr 28, 2006·The British Journal of Radiology·T Suwatanapongched, D S Gierada
Jul 21, 2006·The British Journal of Radiology·M Båth, L G Månsson
Sep 27, 2007·Journal of Computer Assisted Tomography·Su Yeon YouJeung Hee Moon
Feb 6, 2008·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Vincent Chong
Jun 27, 2008·Investigative Radiology·Takeshi NakauraYasuyuki Yamashita
Sep 2, 2008·Journal of Ethnopharmacology·Mohammad HudaibTalal Aburjai
Oct 12, 2010·Computer Methods and Programs in Biomedicine·Peicong YuChueh Loo Poh
Feb 24, 2011·AJR. American Journal of Roentgenology·Markus WeiningerU Joseph Schoepf
Jun 7, 2011·Medical Image Analysis·Marco FeuersteinKensaku Mori
Jan 25, 2012·IEEE Transactions on Medical Imaging·Yang SongDavid Dagan Feng
May 26, 2012·Radiology·Takeshi NakauraYasuyuki Yamashita
Jun 27, 2012·AJR. American Journal of Roentgenology·Eun-Suk ChoKyung Hee Lee
Oct 24, 2012·European Journal of Radiology·Charbel SaadePatrick Brennan
Jun 5, 2013·European Radiology·Charbel SaadePatrick Brennan
Sep 21, 2013·Journal of Computer Assisted Tomography·Charbel SaadePatrick C Brennan
Sep 14, 2014·European Radiology·Hamid BayanatiCarole Dennie
Jun 3, 2015·Journal of Computer Assisted Tomography·LiFang PangJing Yan
Dec 2, 2015·Radiology·Charbel SaadeDavid Yousem
Dec 17, 2015·Advances in Experimental Medicine and Biology·Lindsey A TorreAhmedin Jemal
Jan 6, 2016·Diagnostic and Interventional Radiology : Official Journal of the Turkish Society of Radiology·Charbel SaadeFadi El-Merhi
Feb 9, 2016·Journal of Computer Assisted Tomography·Charbel SaadeFadi El-Merhi
Mar 15, 2016·AJR. American Journal of Roentgenology·Yuji IyamaYasuyuki Yamashita
Oct 19, 2016·Journal of Computer Assisted Tomography·Charbel SaadeLena Naffaa
May 20, 2018·BMC Surgery·Jelle E BousemaUNKNOWN MEDIASTrial study group
Citations
Mar 21, 2020·Journal of Computer Assisted Tomography·Charbel SaadeLena Naffaa
Jul 17, 2020·La Radiologia medica·Charbel SaadeAlain S Abi-Ghanem
Aug 21, 2019·The British Journal of Radiology·Tomoya SekiguchiYuta Shibamoto
Aug 13, 2021·Insights Into Imaging·Julien BurelMatthieu Demeyere